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    Glossary Hypothalamic-Pituitary-Gonadal Axis

    regulates reproductive hormones through interactions between brain and gonads

    The Hypothalamic-Pituitary-Gonadal (HPG) Axis is a complex set of interactions among the hypothalamus, pituitary gland, and gonads (ovaries in females and testes in males) that regulate reproductive function and hormone production. This system controls the release of hormones like GnRH (gonadotropin-releasing hormone), LH (luteinizing hormone), and FSH (follicle-stimulating hormone), which are crucial for processes such as puberty, menstrual cycles, and sperm production.

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    1. Sex differences in the hypothalamic–pituitary–adrenal axis’ response to stress: an important role for gonadal hormones Neuropsychopharmacology · 2019 · 197 citations
    2. Physiology of the Hypothalamic Pituitary Gonadal Axis in the Male Urologic Clinics of North America · 2016 · 70 citations
    3. Age-related changes in endogenous glucocorticoids, gonadal steroids, endocannabinoids and their ratios in plasma and hair from the male C57BL/6 mice General and comparative endocrinology · 2020 · 11 citations
    4. Gonadal Sex Steroids: Production, Action and Interactions in Mammals InTech eBooks · 2012 · 2 citations
    5. Gonadal Function in Men with Cushing Syndrome 2013 · 1 citations
    6. Testosterone Is a Contraceptive and Should Not Be Used in Men Who Desire Fertility The World Journal of Men's Health · 2019 · 39 citations
    7. Normal Pubertal Development: Part I: The Endocrine Basis of Puberty Pediatrics in Review · 2011 · 37 citations
    8. Studies on changes in the concentration of serum adrenal androgens in pubertal twins European Journal of Endocrinology · 1980 · 30 citations
    9. Neuroendocrine Determinants of Polycystic Ovary Syndrome International Journal of Environmental Research and Public Health · 2022 · 19 citations
    10. Exposure of Xenopus laevis tadpoles to finasteride, an inhibitor of 5-α reductase activity, impairs spermatogenesis and alters hypophyseal feedback mechanisms Journal of Molecular Endocrinology · 2009 · 18 citations
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