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GlossaryGonadotropin-releasing hormone

regulates release of reproductive hormones from the pituitary gland

Gonadotropin-releasing hormone (GnRH) is a key hormone produced in the hypothalamus of the brain. It regulates the release of two other important hormones from the pituitary gland: luteinizing hormone (LH) and follicle-stimulating hormone (FSH). These hormones are crucial for reproductive function, including the development of eggs in ovaries and sperm in testes.

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Three-Month Treatment With a Long-Acting Gonadotropin-Releasing Hormone Agonist of Patients With Benign Prostatic Hyperplasia: Effects on Tissue Androgen Concentration, 5α-Reductase Activity and Androgen Receptor Content

research Three-Month Treatment With a Long-Acting Gonadotropin-Releasing Hormone Agonist of Patients With Benign Prostatic Hyperplasia: Effects on Tissue Androgen Concentration, 5α-Reductase Activity and Androgen Receptor Content

82 citations, February 1989 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism”

A three-month treatment with a GnRH agonist significantly lowered androgen levels and 5α-reductase activity in men with benign prostatic hyperplasia.

research Treatment of Hirsutism with a Gonadotropin-Releasing Hormone Agonist (Nafarelin)

77 citations, October 1986 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism”

Nafarelin may effectively treat excessive hair growth in women by reducing certain hormone levels.

17-Hydroxyprogesterone Responses to Gonadotropin-Releasing Hormone Reveal Distinct Phenotypes of Functional Ovarian Hyperandrogenism and Polycystic Ovary Syndrome

research 17-Hydroxyprogesterone Responses to Gonadotropin-Releasing Hormone Reveal Distinct Phenotypes of Functional Ovarian Hyperandrogenism and Polycystic Ovary Syndrome

42 citations, September 2007 in “The Journal of Clinical Endocrinology and Metabolism”

The research found that polycystic ovary syndrome (PCOS) has two distinct types, with one having more severe hormone and insulin issues.

research Gonadotropin-Releasing Hormone Agonist Treatment in Postmenopausal Women with Hyperandrogenism of Ovarian Origin

36 citations, May 2011 in “The Journal of Clinical Endocrinology & Metabolism”

Treatment with a hormone agonist can reduce excess male hormones in postmenopausal women without surgery.

Gonadotropin Releasing Hormone Agonist (Nafarelin) Test to Differentiate Gonadotropin Deficiency from Constitutionally Delayed Puberty in Teenage Boys: A Clinical Research Center Study

research Gonadotropin Releasing Hormone Agonist (Nafarelin) Test to Differentiate Gonadotropin Deficiency from Constitutionally Delayed Puberty in Teenage Boys: A Clinical Research Center Study

24 citations, October 1995 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism”

The nafarelin test can reliably distinguish between gonadotropin deficiency and delayed puberty in teenage boys.

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community My Testosterone is less than 1/3rd In 7 Months since I took Finasteride!

in Finasteride/Dutasteride 113 upvotes 1 year ago

A user experienced a significant drop in testosterone levels after taking finasteride, leading to side effects like low libido and muscle mass loss. Despite its effectiveness for hair, the user decided to stop finasteride due to its impact on hormones, preferring to be bald.

community 35 MtF | 16 Months | Minoxidil + Dutasteride + Microneedling + Exosomes. Note that since I'm early in my transition (and I was coming from a bald state), I still have short hair. Very few MtF progress pictures here, I figure this might help some of you.

in Transgender 128 upvotes 1 year ago

A 35-year-old transitioning female (MtF) shared her hair regrowth journey using Minoxidil, Dutasteride, Microneedling, and Exosomes, starting from a bald state. Commenters discussed the impressive results, skin care routine, and the effects of estrogen on hair and skin.

community Started Finasteride almost three months ago and I'm upset

in Update 153 upvotes 9 months ago

A user started taking finasteride three months ago to treat hair loss and unexpectedly cleared their acne, which they had been struggling with since age 12. The conversation includes others sharing their experiences with finasteride, its effects on acne and hair loss, and mentions a related treatment, clascoterone, for acne and hair loss.

community Testosterone is 1600, would taking low dose anti-androgens be a viable treatment option for people who’s T spikes on DHT-blockers?

in Treatment 45 upvotes 1 year ago

The post and conversation are about the user's high testosterone levels and their worsening hair loss despite trying various treatments. They are considering using low doses of anti-androgens to lower their testosterone levels as a potential solution.

community Completely defeated after trying so hard with topical finasteride.

in Finasteride/Dutasteride 24 upvotes 1 year ago

A user who has tried multiple treatments for hair loss, including oral and topical finasteride and liposomal finasteride, but experienced severe side effects in each case; the user is considering trying RU58841 or aromatise inhibitors as alternatives.

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