Glucocorticoids and Mineralocorticoids in Hair: Facilitating Accurate Diagnosis of Adrenal-Related Endocrine Disorders

November 2024 in “ Frontiers in Endocrinology ”

Bianca Heyns, Rialet Pieters, Maria A. Stander, Stephen L. Atkin, Amanda C. Swart

glucocorticoids mineralocorticoids hair follicles deoxycortisol deoxycorticosterone aldosterone 18-hydroxycorticosterone hypoaldosteronism primary hyperaldosteronism Cushing’s syndrome congenital adrenal hyperplasia

🚨 The study involves human hair and hormones, which are relevant to hair biology and potentially to hair loss, but it primarily focuses on diagnosing adrenal-related endocrine disorders rather than hair health or hair loss treatments.

Studysummary This study used a novel extraction method to detect and measure mineralocorticoids and glucocorticoids in hair follicles, concluding these steroids may serve as effective biomarkers for diagnosing conditions related to steroid excess or deficiency, such as Cushing’s syndrome and congenital adrenal hyperplasia.

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