In this study, a 37-year-old female with resistant hypertension and signs of Cushing's syndrome and primary aldosteronism was found to have normal cortisol levels but high levels of cortisol and aldosterone via adrenal venous sampling, leading to a diagnosis confirmed by right adrenalectomy.
November 2024 in “Frontiers in Endocrinology” This study used a novel extraction method to detect and measure mineralocorticoids and glucocorticoids in hair follicles, concluding these steroids may serve as effective biomarkers for diagnosing conditions related to steroid excess or deficiency, such as Cushing’s syndrome and congenital adrenal hyperplasia.
January 2020 in “the british journal of cardiology” This case report suggests that the progestogen-only pill may cause false-positive aldosterone/renin ratio results in primary hyperaldosteronism screening, indicating it should be omitted before testing.
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August 2009 in “Journal of Feline Medicine and Surgery” In this case report, a 14-year-old cat was diagnosed with both hyperaldosteronism and hyperprogesteronism linked to a large adrenal tumor, highlighting the importance for clinicians to consider these concurrent conditions in similar cases.
February 2024 in “Practical Diabetes” This study showed that spironolactone effectively reduces morbidity and mortality in moderate to severe heart failure with reduced ejection fraction, but its benefits in heart failure with preserved ejection fraction are less clear.
