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    Glossary Deoxycorticosterone

    steroid hormone regulating salt and water balance in kidneys

    Deoxycorticosterone (DOC) is a steroid hormone produced by the adrenal glands. It plays a role in regulating salt and water balance in the body by acting on the kidneys to promote sodium retention and potassium excretion. This hormone is a precursor in the biosynthesis of aldosterone, another key hormone involved in electrolyte and fluid balance.

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    1. Stress-Induced Deoxycorticosterone-Derived Neurosteroids Modulate GABA<sub>A</sub>Receptor Function and Seizure Susceptibility Journal of Neuroscience · 2002 · 269 citations
    2. The Acute Anticonvulsant Effects of Deoxycorticosterone in Developing Rats: Role of Metabolites and Mineralocorticoid‐receptor Responses Epilepsia · 2005 · 13 citations
    3. Deoxycorticosterone’s anticonvulsant effects in infant rats are blocked by finasteride, but not by indomethacin Experimental Neurology · 2006 · 7 citations
    4. Finasteride inhibits the disease-modifying activity of progesterone in the hippocampus kindling model of epileptogenesis Epilepsy & Behavior · 2012 · 26 citations
    5. Relating neurosteroid modulation of inhibitory neurotransmission to behaviour Journal of Neuroendocrinology · 2021 · 18 citations
    6. The role of the adrenal glands in regulating onset of winter fur growth in mink (<i>Mustela vison</i>) 1992 · 16 citations
    7. Replacement with GABAergic steroid precursors restores the acute ethanol withdrawal profile in adrenalectomy/gonadectomy mice Neuroscience · 2009 · 12 citations
    8. Bilateral adrenalectomy induces early onset of summer fur growth in mink (Mustela vison) 1995 · 5 citations
    9. Glucocorticoids and mineralocorticoids in hair: facilitating accurate diagnosis of adrenal-related endocrine disorders Frontiers in Endocrinology · 2024
    10. Neurosteroids as Endogenous Regulators of Seizure Susceptibility 2002
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    1. Trying to understand finasteride side effects and post finasteride syndrome Reddit · 31 Oct 2020

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