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    Glossary Deoxycorticosterone

    steroid hormone regulating salt and water balance in kidneys

    Deoxycorticosterone (DOC) is a steroid hormone produced by the adrenal glands. It plays a role in regulating salt and water balance in the body by acting on the kidneys to promote sodium retention and potassium excretion. This hormone is a precursor in the biosynthesis of aldosterone, another key hormone involved in electrolyte and fluid balance.

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    Research 30 of 194

    1. Stress-Induced Deoxycorticosterone-Derived Neurosteroids Modulate GABA<sub>A</sub>Receptor Function and Seizure Susceptibility Journal of Neuroscience · 2002 · 269 citations
    2. The Acute Anticonvulsant Effects of Deoxycorticosterone in Developing Rats: Role of Metabolites and Mineralocorticoid‐receptor Responses Epilepsia · 2005 · 13 citations
    3. Deoxycorticosterone’s anticonvulsant effects in infant rats are blocked by finasteride, but not by indomethacin Experimental Neurology · 2006 · 7 citations
    4. Finasteride inhibits the disease-modifying activity of progesterone in the hippocampus kindling model of epileptogenesis Epilepsy & Behavior · 2012 · 26 citations
    5. Relating neurosteroid modulation of inhibitory neurotransmission to behaviour Journal of Neuroendocrinology · 2021 · 18 citations
    6. The role of the adrenal glands in regulating onset of winter fur growth in mink (<i>Mustela vison</i>) 1992 · 16 citations
    7. Replacement with GABAergic steroid precursors restores the acute ethanol withdrawal profile in adrenalectomy/gonadectomy mice Neuroscience · 2009 · 12 citations
    8. Bilateral adrenalectomy induces early onset of summer fur growth in mink (Mustela vison) 1995 · 5 citations
    9. Glucocorticoids and mineralocorticoids in hair: facilitating accurate diagnosis of adrenal-related endocrine disorders Frontiers in Endocrinology · 2024
    10. Neurosteroids as Endogenous Regulators of Seizure Susceptibility 2002
    11. THE ENDOCRINE SYSTEM AND HAIR GROWTH IN THE RAT Journal of Endocrinology · 1942 · 28 citations
    12. THE EFFECTS OF THE SYNTHETIC AND NATURAL HORMONE OF THE ADRENAL CORTEX ON MELANIN DEPOSITION IN ADRENALECTOMIZED BLACK RATS FED DIETS ADEQUATE AND DEFICIENT IN THE FILTRATE FACTORS OF VITAMIN B<sup>1</sup> Endocrinology · 1945 · 27 citations
    13. Urinary steroid metabolome shows adrenal, gonadal, and neuroactive steroid dysregulation in adolescents with depression 2025 · 1 citations
    14. Study on Changes of 19 Steroids in Plasma From 9 Diagnosed Patients With P450 Oxidoreductase Deficiency Research Square (Research Square) · 2021
    15. Studies on Neurosteroids XXV. Influence of a 5.ALPHA.-Reductase Inhibitor, Finasteride, on Rat Brain Neurosteroid Levels and Metabolism Biological & Pharmaceutical Bulletin · 2008 · 61 citations
    16. Role of prolactin in regulating the onset of winter fur growth in mink (Mustela vison): A reconsideration 1999 · 12 citations
    17. Neuroactive Steroids and Ethanol Exposure: Relevance to Ethanol Sensitivity and Alcohol Use Disorders Risk Elsevier eBooks · 2019 · 1 citations
    18. Results of clinical examinations, laboratory tests, and ultrasonography in dogs with pituitary-dependent hyperadrenocorticism treated with trilostane American journal of veterinary research · 2002 · 116 citations
    19. EMQN best practice guidelines for molecular genetic testing and reporting of 21-hydroxylase deficiency European Journal of Human Genetics · 2020 · 94 citations
    20. The Dark Side of 5α-Reductase Inhibitors' Therapy: Sexual Dysfunction, High Gleason Grade Prostate Cancer and Depression Korean Journal of Urology · 2014 · 75 citations
    21. Effects of 5-alpha reductase inhibitors on erectile function, sexual desire and ejaculation Expert Opinion on Drug Safety · 2012 · 71 citations
    22. Skin steroidogenesis in health and disease Reviews in endocrine and metabolic disorders · 2016 · 47 citations
    23. Realising the therapeutic potential of neuroactive steroid modulators of the GABAA receptor Neurobiology of Stress · 2019 · 40 citations
    24. Management of CAH during pregnancy Current Opinion in Endocrinology, Diabetes and Obesity · 2012 · 29 citations
    25. Finasteride-induced depression: new insights into possible pathomechanisms Journal of Cosmetic Dermatology · 2010 · 22 citations
    26. Neuropsychological Assessment in Elderly Men with Benign Prostatic Hyperplasia Treated with Dutasteride Clinical Drug Investigation · 2018 · 20 citations
    27. Hirsutism in the Adolescent Female 1989 · 13 citations
    28. Is there a role for 5α‐reductase inhibitors in transgender individuals? International Journal of Andrology · 2020 · 10 citations
    29. Influence of sex and functional status on the value of serum steroid profiling in discriminating adrenocortical carcinoma from adrenocortical adenoma Frontiers in Endocrinology · 2024 · 4 citations
    30. Cardiometabolic risk factors in women with non-classic congenital adrenal hyperplasia Acta Cardiologica · 2019 · 2 citations