Neuropsychological Assessment in Elderly Men with Benign Prostatic Hyperplasia Treated with Dutasteride

    October 2018 in “ Clinical Drug Investigation
    Antonino Catalano, Gabriella Martino, Federica Bellone, Maria Papalia, Carmen Lasco, Giorgio Basile, Alberto Sardella, Giacomo Nicocia, Nunziata Morabito, Antonino Lasco
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    TLDR Dutasteride does not impair mental function in elderly men with enlarged prostate.
    The study examined the potential neuropsychological effects of dutasteride, a drug used to treat benign prostatic hyperplasia (BPH), on elderly men. It included 40 participants with an average age of 71.4 years, split into two groups: one receiving dutasteride and a control group not on the medication. After administering various neuropsychological tests, the researchers found no significant differences in outcomes between the two groups, suggesting that dutasteride does not cause neuropsychological impairment. Despite the study's small sample size and cross-sectional design, the findings indicate that dutasteride is mentally safe for treating BPH in elderly men, but further research is recommended to confirm these results.
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