Treatment of Nonclassic 11-Hydroxylase Deficiency with Ashwagandha Root

Oral minoxidil is effective for hair loss and unlikely to significantly affect collagen synthesis, making it a safe option without causing premature skin aging. Users report positive hair regrowth without noticeable skin aging.

Oral copper supplementation significantly improved hair regrowth for someone who experienced severe hair loss after stopping minoxidil, suggesting copper deficiency might hinder minoxidil's effectiveness. The user now only takes copper and occasionally uses microneedling, recommending others to try copper if minoxidil alone isn't effective.

Oral ketoconazole is discussed as a potential hair loss treatment, but it poses significant health risks like liver damage and adrenal insufficiency. Users suggest safer alternatives like topical anti-androgens or spironolactone, emphasizing the importance of consulting a specialist.

The user experienced side effects from minoxidil, including hirsutism and facial changes, and switched to castor oil, which has not caused similar side effects. They continue using microneedling and dutasteride, reporting minor hair shedding but no significant hair loss.

Dutasteride may reduce bone mineral density, but there's no increased risk of osteoporosis or fractures compared to finasteride. Users suggest resistance training to counter potential bone effects.

Minoxidil may inhibit androgen receptors and affect hormonal pathways, potentially explaining its effectiveness in treating androgenetic alopecia (AGA). Users discuss its varying effectiveness on scalp versus facial hair and note fewer side effects with topical use compared to oral.