TLDR Ashwagandha root improved symptoms of nonclassic 11-hydroxylase deficiency in an elderly woman.
The document discussed the treatment of nonclassic 11-hydroxylase deficiency using Ashwagandha root, highlighting a case of a 78-year-old woman who showed significant improvement in symptoms such as acne and alopecia over three years. The treatment normalized her serum 11-deoxycortisol levels and improved her hair loss and acne, suggesting a dose-related effect of Ashwagandha. The study proposed Ashwagandha as a potential alternative treatment for nonclassic 11-hydroxylase deficiency, offering a natural option with fewer side effects, and emphasized the need for further research to confirm these findings. The treatment was well-tolerated without significant changes in vital signs or laboratory parameters.
5 citations,
March 2013 in “BMJ case reports” Gastric bypass surgery improved a woman's hormonal disorder without the need for medication.
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September 2012 in “BMJ case reports” Ashwagandha may improve hormone levels and reduce hair loss in non-classical adrenal hyperplasia.
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September 2012 in “BMJ case reports” Ashwagandha may improve hormone levels and reduce hair loss in non-classical adrenal hyperplasia.
April 2019 in “Journal of the Endocrine Society” An over-the-counter vitamin/mineral supplement improved hair loss and blood sugar control in a woman with non-classic 11-hydroxylase deficiency.
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December 2022 in “Frontiers in Endocrinology” Treating non-classic congenital adrenal hyperplasia is complex because the benefits of hormone treatment must be weighed against potential health risks.
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March 2013 in “BMJ case reports” Gastric bypass surgery improved a woman's hormonal disorder without the need for medication.
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August 2008 in “Reviews in endocrine and metabolic disorders” Nonclassic adrenal hyperplasia is a genetic condition that can cause early puberty and fertility problems, treated with specific steroids.