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research Treatment of Nonclassic 11-Hydroxylase Deficiency with Ashwagandha Root

2 citations , January 2017 in “Case reports in endocrinology”

This report describes an elderly woman whose nonclassic 11-hydroxylase deficiency, presenting as acne and male pattern alopecia, may have been ameliorated by Ashwagandha root in a dose-related manner.

research Screening for 21-hydroxylase–deficient nonclassic adrenal hyperplasia among hyperandrogenic women: a prospective study

216 citations , November 1999 in “Fertility and Sterility”

This study found that a basal 17-hydroxyprogesterone level is effective for screening nonclassic adrenal hyperplasia in women, with a 4 ng/mL cutoff providing high specificity and positive predictive value.

An Update on Congenital Adrenal Hyperplasia

research An Update of Congenital Adrenal Hyperplasia

151 citations , December 2004 in “Annals of the New York Academy of Sciences”

This review discusses nonclassical 21-hydroxylase deficiency as the most common autosomal recessive disorder in humans and highlights the effectiveness of glucocorticoid treatment in reversing related symptoms.

Hyperandrogenism in Adolescent Girls: Diagnosis and Management

research Hyperandrogenism in Adolescent Girls

10 citations , January 2004 in “KARGER eBooks”

This article reviews the differential diagnosis of mild hyperandrogenism in adolescent girls, discussing potential causes such as PCOS and nonclassic adrenal hyperplasia, but presents no new data.

research Genetics and Pathophysiology of Congenital Adrenal Hyperplasia

July 2017 in “Contemporary Endocrinology”

This article discusses the ongoing care needs for individuals with 21-hydroxylase deficiency due to mutations in the CYP21A2 gene but does not present new clinical findings.

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