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    Research 10 of 542

    1. Human hair follicles display a functional equivalent of the hypothalamic‐pituitary‐adrenal (HPA) axis and synthesize cortisol The FASEB Journal · 2005 · 489 citations
    2. Maternal Influence on Child HPA Axis: A Prospective Study of Cortisol Levels in Hair PEDIATRICS · 2013 · 122 citations
    3. HPA axis stress reactivity and hair cortisol concentrations in recently detoxified alcoholics and healthy controls with and without childhood maltreatment Addiction Biology · 2018 · 24 citations
    4. The human hair follicle has established a fully functional peripheral equivalent of the hypothamalic‐pituitary‐adrenal‐axis (HPA) Experimental Dermatology · 2005 · 9 citations
    5. Localized alopecia and suppression of hypothalamic-pituitary-adrenal (HPA) axis in dogs following treatment with difluprednate 0.05% ophthalmic emulsion (Durezol®) BMC veterinary research · 2021 · 2 citations
    6. HPA Axis Variation and ACEs; Childhood Sexual Trauma is Associated with Lower Hair Cortisol in Adulthood Psychoneuroendocrinology · 2023 · 1 citations
    7. Allopregnanolone (AP) induces opioid inhibition of hypothalamo-pituitary-adrenal (HPA) axis responses to interleukin-1β (IL-1β) in pregnancy Experimental and Clinical Endocrinology & Diabetes · 2005 · 1 citations
    8. Does hair cortisol concentration reflect measurable regulatory biology of the HPA axis in healthy humans? Psychoneuroendocrinology · 2026
    9. Testosterone’s regulation of the HPA axis differs for adolescent and adult male rats Brock University Digital Repository (Brock University) · 2018
    10. New effects of caffeine on corticotropin‐releasing hormone (CRH)‐induced stress along the intrafollicular classical hypothalamic–pituitary–adrenal (HPA) axis (CRH‐R1/2, IP<sub>3</sub>‐R, ACTH, MC‐R2) and the neurogenic non‐HPA axis (substance P, p75<sup>NTR</sup>and TrkA) in<i>ex vivo</i>human male androgenetic scalp hair follicles British Journal of Dermatology · 2020 · 12 citations
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    Community 6

    1. Mechanism of action of alfatradiol (17 alpha estradiol) Reddit · 29 May 2024
    2. Is there a topical androgen receptor blocker so we don't have to fuck with the enzyme and destroy our allopregnanolone, but go and hit the end target straight? Reddit · 22 May 2024
    3. Clascoterone study going on right now Reddit · 26 Apr 2024
    4. CB-03-01 / Breezula Personal Results Reddit · 10 Feb 2026
    5. EMA is re-examining Winlevi (clascoterone at lower concentration) Reddit · 1 Jul 2025
    6. There’s actually a quite good chance that next year, we might see a new treatment get FDA approval for the first time in nearly three decades. Reddit · 4 Feb 2025

    Learn 2

    1. Clascoterone Topical androgen-receptor blocker, approved as an acne cream
    2. Hydrocortisone Mild corticosteroid used on the skin and scalp