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GlossaryCorticosteroids (Glucocorticoid)

hormones reducing inflammation and immune response, often prescribed for autoimmune diseases

Corticosteroids are a class of steroid hormones that are produced in the adrenal cortex and are used in medicine to reduce inflammation and suppress the immune system. They are commonly prescribed for conditions like asthma, arthritis, and autoimmune diseases, and can be administered in various forms, including oral pills, topical creams, and injections.

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research Glucocorticoid Corticosteroids for Duchenne Muscular Dystrophy

407 citations , January 2008 in “Cochrane Database of Systematic Reviews”

Glucocorticoid corticosteroids improve muscle strength in Duchenne muscular dystrophy but can cause side effects.

research Altered Skin Development and Impaired Proliferative and Inflammatory Responses in Transgenic Mice Overexpressing the Glucocorticoid Receptor

92 citations , July 2001 in “The FASEB Journal”

Overexpressing the glucocorticoid receptor in mice leads to abnormal skin development and reduced inflammation.

A Novel Point Mutation in the Ligand-Binding Domain of the Human Glucocorticoid Receptor Causing Generalized Glucocorticoid Resistance: The Importance of the C Terminus in Conferring Transactivational Activity

research A Novel Point Mutation in the Ligand-Binding Domain of the Human Glucocorticoid Receptor Causing Generalized Glucocorticoid Resistance: The Importance of the C Terminus in Conferring Transactivational Activity

91 citations , May 2005 in “The Journal of Clinical Endocrinology & Metabolism”

A new mutation in the human glucocorticoid receptor reduces its function and causes resistance to glucocorticoids.

research Large Doses of Glucocorticoid in the Treatment of Alopecia Areata

80 citations , November 1975 in “Acta dermato-venereologica”

Large doses of glucocorticoids are not suitable for general use in treating severe alopecia areata due to inconsistent results and risks.

research Glucocorticoid Effect on Hair Growth Initiation: A Reconsideration

77 citations , January 1993 in “Skin Pharmacology and Physiology”

Steroids stop hair growth temporarily but don't block the signals that start it.

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community We Need A Solution For The Inflammatory Response related To AGA

in Research/Science 16 upvotes 1 year ago

The conversation is about finding a solution for scalp inflammation related to AGA, with the user expressing frustration that Minoxidil and Finasteride do not address inflammation. The user has researched glucocorticoids and topical NSAIDs for reducing inflammation and seeks advice from specialists.

community Thoughts about ORAL ketoconazole? (pills)

in Ketoconazole 23 hours ago

Oral ketoconazole is discussed as a potential hair loss treatment, but it poses significant health risks like liver damage and adrenal insufficiency. Users suggest safer alternatives like topical anti-androgens or spironolactone, emphasizing the importance of consulting a specialist.

community AA and Hirsutism but T levels are normal

in Female 6 upvotes 4 years ago

27-year-old female experiences aggressive hair thinning and hirsutism despite normal testosterone levels. Spironolactone and 2% minoxidil were ineffective; high DHEA sulfate levels may be the cause.

community New and Interesting HairLoss Studies/Papers/Reviews

in Treatment 43 upvotes 5 years ago

Hair loss treatments discussed include Dutasteride with Ketoconazole, tissue engineering strategies, and androgenetic alopecia therapies. Massage doubles follicular retention, improving treatment effectiveness.

community No luck with meds, Check your Cortisol.

in Treatment 34 upvotes 1 year ago

Cortisol from stress can cause hair loss. Controlling cortisol levels improved the effectiveness of finasteride for hair regrowth.

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