Self-Assembly of Solubilized Human Hair Keratins

    Hui Ying Lai, Magdiel Inggrid Setyawati, Abdul Rahim Ferhan, Shiva Kamini Divakarla, Huei Min Chua, Nam‐Joon Cho, Wojciech Chrzanowski, Kee Woei Ng
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    TLDR Human hair keratins can form stable nanofiber networks that might help in tissue regeneration.
    The study demonstrated that keratins extracted from human hair can self-assemble into nanoscale intermediate filaments, forming dense, homogeneous, and continuous nanofibrous networks. These networks were shown to be hydrolytically stable for up to 5 days in cell culture media and compatible with primary human dermal fibroblasts and keratinocytes. This finding suggests that human hair keratins have potential for use in regenerative applications where structured assembly is advantageous.
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