Evaluating the Antioxidant Effects of Human Hair Protein Extracts

December 2017 in “ Journal of biomaterials science. Polymer ed. ”

Hui Ying Lai, Shuai Wang, Vaishali Singh, Luong Nguyen, Kee Woei Ng

human hair protein extracts antioxidant effects human dermal fibroblasts cysteine oxidative stress reactive oxygen species H2O2 HDFs ROS hydrogen peroxide

TLDR Human hair protein extracts can protect skin cells from oxidative stress.

The study evaluated the antioxidant effects of human hair protein extracts, highlighting their potential to protect human dermal fibroblasts (HDFs) from oxidative stress. The extracts, rich in cysteine (11.2 mol %), were characterized using various biochemical techniques and demonstrated significant antioxidant activity (IC50 = 16.22 μM). When added to cell culture media, the extracts maintained cell viability and reduced reactive oxygen species production in HDFs exposed to H2O2. These findings suggested that human hair protein extracts could be used in biomedical applications for their antioxidizing properties.

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