Image

    Hair Follicles as a Critical Model for Monitoring the Circadian Clock

    January 2023 in “ International Journal of Molecular Sciences ”
    Li-Ping Liu, Meng-Huan Li, Yun‐Wen Zheng
    Studysummary This review discusses the expression of circadian genes in hair follicles and their potential for monitoring circadian-rhythm-related conditions, reporting no clinical results; the authors suggest combining hair sampling with other assessments for better insight.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
    Read the full study on mdpi.com →
    Discuss this study in the Community →

    Research cited in this study 32

    1. Morphogenesis, Growth Cycle, and Molecular Regulation of Hair Follicles Frontiers in Cell and Developmental Biology · 2022
    2. Revisiting the Role of Melatonin in Human Melanocyte Physiology: A Skin Context Perspective Journal of pineal research · 2022
    3. Prevalence of Early-Onset Androgenetic Alopecia and Its Relation with Lifestyle and Dietary Habits Italian journal of dermatology and venereology · 2022
    4. Disturbance of the Circadian System in Shift Work and Its Health Impact Journal of biological rhythms · 2021
    5. Psychology of Hair Loss Patients and Importance of Counseling Indian Journal of Plastic Surgery · 2021
    6. Health-Related Quality of Life, Depression, and Self-Esteem in Patients With Androgenetic Alopecia JAMA Dermatology · 2021
    7. Telomere Dynamics and Telomerase in the Biology of Hair Follicles and Their Stem Cells as a Model for Aging Research Journal of Investigative Dermatology · 2021
    8. Topical L-Thyroxine: The Cinderella Among Hormones Waiting to Dance on the Floor of Dermatological Therapy? Experimental Dermatology · 2020
    9. The Effect of Night Shift Work on the Expression of Clock Genes in Beard Hair Follicle Cells Sleep medicine · 2019
    10. Human Long-Term Deregulated Circadian Rhythm Alters Regenerative Properties of Skin and Hair Precursor Cells European journal of dermatology/EJD. European journal of dermatology · 2018
    11. External Light Activates Hair Follicle Stem Cells Through Eyes Via an ipRGC–SCN–Sympathetic Neural Pathway Proceedings of the National Academy of Sciences of the United States of America · 2018
    12. A Simple Method Using Ex Vivo Culture of Hair Follicle Tissue to Investigate Intrinsic Circadian Characteristics in Humans Scientific reports · 2017
    13. Molecular Insights Into Chronotype and Time-of-Day Effects on Decision-Making Scientific reports · 2016
    14. Estimation Methods for Human Circadian Phase Using Peripheral Tissues Hypertension research · 2016
    15. Peripheral Skin Temperature and Circadian Biological Clock in Shift Nurses After a Day Off International journal of molecular sciences · 2016
    16. Hair Follicle Aging Is Driven by Transepidermal Elimination of Stem Cells via COL17A1 Proteolysis Science · 2016
    17. Thyroxine Differentially Modulates the Peripheral Clock: Lessons from the Human Hair Follicle PLoS ONE · 2015
    18. When The Circadian Clock Meets The Melanin Pigmentary System Journal of Investigative Dermatology · 2015
    19. The Peripheral Clock Regulates Human Pigmentation ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2014
    20. Possible Contribution of Chronobiology to Cardiovascular Health Frontiers in physiology · 2014
    21. A Meeting of Two Chronobiological Systems: Circadian Proteins Period1 and BMAL1 Modulate the Human Hair Cycle Clock Journal of Investigative Dermatology · 2013
    22. An Out-Of-Lab Trial: A Case Example For The Effect Of Intensive Exercise On Rhythms Of Human Clock Gene Expression Journal of circadian rhythms · 2013
    23. The Clock Gene Brain And Muscle Arnt-Like Protein-1 (BMAL1) Is Involved In Hair Growth Archives of Dermatological Research · 2013
    24. Local Circadian Clock Gates Cell Cycle Progression of Transient Amplifying Cells During Regenerative Hair Cycling Proceedings of the National Academy of Sciences of the United States of America · 2013
    25. Brain And Muscle Arnt-Like Protein-1 (BMAL1) Controls Circadian Cell Proliferation And Susceptibility To UVB-Induced DNA Damage In The Epidermis Proceedings of the National Academy of Sciences of the United States of America · 2012
    26. The Circadian Molecular Clock Creates Epidermal Stem Cell Heterogeneity Nature · 2011
    27. Noninvasive Method for Assessing the Human Circadian Clock Using Hair Follicle Cells Proceedings of the National Academy of Sciences of the United States of America · 2010
    28. The Cycling Hair Follicle as an Ideal Systems Biology Research Model Experimental Dermatology · 2010
    29. The Hair Follicle as a Dynamic Mini-Organ Current Biology · 2009
    30. Thyroid Hormones Directly Alter Human Hair Follicle Functions: Anagen Prolongation and Stimulation of Both Hair Matrix Keratinocyte Proliferation and Hair Pigmentation The Journal of Clinical Endocrinology & Metabolism · 2008
    31. The Hair Cycle Journal of Cell Science · 2006
    32. Conditional Telomerase Induction Causes Proliferation of Hair Follicle Stem Cells Nature · 2005

    Related research 1

    1. Hair Follicles as a Critical Model for Monitoring the Circadian Clock International Journal of Molecular Sciences · 2023