The Effect of Night Shift Work on the Expression of Clock Genes in Beard Hair Follicle Cells

The study investigated the impact of night shift work on the expression of clock genes in beard hair follicle cells among Japanese men. It found that the expression of Period3 and Nr1d2 genes followed a more consistent 24-hour rhythm in the daytime and one-night groups compared to the consecutive-night group, with overall Period3 expression significantly lower in the consecutive-night group. These findings suggested that night shift work disrupted circadian rhythms and clock gene expression, with variations depending on the shift schedule and individual differences.