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research Rhythmic expression of circadian clock genes in human leukocytes and beard hair follicle cells

38 citations , August 2012 in “Biochemical and biophysical research communications”

This study found that leukocytes and beard hair follicle cells have an endogenous circadian clock, with PER1 and PER3 expression possibly serving as biomarkers for assessing individual biological clock traits.

research The effect of night shift work on the expression of clock genes in beard hair follicle cells

12 citations , January 2019 in “Sleep medicine”

This study found that night shift work disrupts clock gene expression in Japanese men, particularly affecting rhythms and levels of Period3 and Nr1d2, based on the shift schedule.

research Peripheral Skin Temperature and Circadian Biological Clock in Shift Nurses after a Day off

49 citations , April 2016 in “International journal of molecular sciences”

This study found that shift nurses exhibited lower circadian variations compared to daytime nurses, indicating an adjustment of their biological clocks to continuous shift schedules.

research Investigation of a non-invasive method of assessing the equine circadian clock using hair follicle cells

15 citations , October 2012 in “Journal of circadian rhythms”

This study found that extracting RNA from equine hair follicles can effectively identify 24-hour oscillations of specific circadian clock genes, offering a valuable non-invasive method to evaluate the equine circadian clock.

research Molecular insights into chronotype and time-of-day effects on decision-making

36 citations , July 2016 in “Scientific reports”

This study found that decision-making effects related to time of day and chronotype were only significant when using RNA-based chronotype measurements, indicating molecular clock differences may influence these behaviors.

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Community Join

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community Minoxidil aint shit, genetics are dumb, i dont want to be bald

in Minoxidil 217 upvotes 11 months ago

Minoxidil alone is not effective for significant hair regrowth; combining it with finasteride or dutasteride is necessary. Additional treatments like hair transplants, microneedling, or oral medications are recommended for better results.

community Why I Take 5mg Minoxidil at Night Instead of Splitting 2.5mg

9 upvotes 3 months ago

Taking 5mg oral minoxidil at night instead of splitting 2.5mg doses, with the rationale that a single larger dose may provide a stronger activation for hair follicles and reduce peak-related side effects. Some users report sleep issues with nighttime dosing, while others find it beneficial; opinions on effectiveness and side effects vary.

community So it turns out Post Finasteride Syndrome was never real?

in Finasteride/Dutasteride 271 upvotes 2 years ago

Post Finasteride Syndrome (PFS) is debated, with some users reporting severe side effects from finasteride, while others believe these effects are rare or psychosomatic. Treatments discussed include finasteride, minoxidil, and RU58841.

community I just got one of these. Let's see how it goes...

in Technology 263 upvotes 6 months ago

Red light therapy for hair loss is controversial, with mixed results reported. Its effectiveness may depend on device quality and proper wavelength, and it is often used with minoxidil and finasteride.

community One year off fin/min and I regret it

416 upvotes 1 year ago

The user regrets stopping finasteride and minoxidil due to side effects but plans to resume treatment. They consider using finasteride every other day and continuing topical minoxidil to manage side effects while maintaining hair.

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Experts

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Hair System Specialist
Jane Genesi
Marlton, PA, United States

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Jane Genesi