Image

    Age-Related Changes in Female Scalp Dermal Sheath and Dermal Fibroblasts: How the Hair Follicle Environment Impacts Hair Aging

    December 2020 in “ Journal of Investigative Dermatology ”
    Rachael Williams, Gillian Westgate, Alison D. Pawlus … M. Julie Thornton
    Studysummary This study observed that aging leads to significant structural and biological changes in the scalp's hair follicle environment in women, which may affect hair growth.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
    Read the full study on jidonline.org →
    Discuss this study in the Community →

    Research cited in this study 38

    1. Distinct Regulatory Programs Control the Latent Regenerative Potential of Dermal Fibroblasts During Wound Healing Cell stem cell · 2020
    2. Getting Under the Skin of Hair Aging: The Impact of the Hair Follicle Environment Experimental Dermatology · 2020
    3. Lineage Identity and Location Within the Dermis Determine the Function of Papillary and Reticular Fibroblasts in Human Skin Journal of Investigative Dermatology · 2018
    4. Cellular Therapy with Human Autologous Adipose-Derived Adult Cells of Stromal Vascular Fraction for Alopecia Areata Stem Cell Research & Therapy · 2018
    5. 5α-Reductase Isozymes and Aromatase mRNA Levels in Plucked Hair from Young Women with Female Pattern Hair Loss Archives of Dermatological Research · 2017
    6. What Ages Hair? International Journal of Women's Dermatology · 2017
    7. Hair Follicle Aging Is Driven by Transepidermal Elimination of Stem Cells via COL17A1 Proteolysis Science · 2016
    8. Female Pattern Hair Loss: A Clinical and Pathophysiological Review Anais Brasileiros De Dermatologia · 2015
    9. Hair Follicle Dermal Stem Cells Regenerate the Dermal Sheath, Repopulate the Dermal Papilla, and Modulate Hair Type Developmental Cell · 2014
    10. Resting No More: Redefining Telogen, the Maintenance Stage of the Hair Growth Cycle Biological Reviews · 2014
    11. Distinct Fibroblast Lineages Determine Dermal Architecture in Skin Development and Repair Nature · 2013
    12. Estrogens and Aging Skin Dermato-endocrinology · 2013
    13. The Biology of Hair Diversity International Journal of Cosmetic Science · 2013
    14. Immunohistochemical Patterns in the Interfollicular Caucasian Scalps: Influences of Age, Gender, and Alopecia BioMed Research International · 2013
    15. Cartilage Oligomeric Matrix Protein Forms Part of the Connective Tissue of Normal Human Hair Follicles Experimental dermatology · 2011
    16. How Real Is Senescent Alopecia? A Histopathologic Approach Clinics in Dermatology · 2010
    17. Investigation of Aging Effects in Human Hair Using Atomic Force Microscopy Skin Research and Technology · 2010
    18. Hair Loss in Elderly Women: A Dermatological Concern European Journal of Dermatology · 2010
    19. Histopathology of Alopecia: A Clinicopathological Approach to Diagnosis Histopathology · 2009
    20. Review of Hair Follicle Dermal Cells Journal of Dermatological Science · 2009
    21. Ultraviolet Light-Induced Leukoderma of the Scalp Associated with Androgenetic Alopecia: Senescent Actinic Depigmentation of the Scalp Journal of Cutaneous Medicine and Surgery · 2009
    22. Androgens and Hair Growth Dermatologic Therapy · 2008
    23. Follicular Streamers (Stelae) in Scarring and Non-Scarring Alopecia Journal of Cutaneous Pathology · 2008
    24. Effect of Estrogens on Skin Aging and the Potential Role of SERMs Clinical Interventions in Aging · 2007
    25. The Modulation of Aromatase and Estrogen Receptor Alpha in Cultured Human Dermal Papilla Cells by Dexamethasone: A Novel Mechanism for Selective Action of Estrogen via Estrogen Receptor Beta? Journal of Investigative Dermatology · 2006
    26. Estrogen Functions in Skin and Skin Appendages Expert Opinion on Therapeutic Targets · 2005
    27. Hair Cycle-Specific Expression of Versican in Human Hair Follicles Journal of Dermatological Science · 2005
    28. The Lack of Significant Changes in Scalp Hair Follicle Density With Advancing Age British Journal of Dermatology · 2005
    29. Cell Movement in the Hair Follicle Dermis: More Than a Two-Way Street? Journal of Investigative Dermatology · 2003
    30. Cultured Peribulbar Dermal Sheath Cells Can Induce Hair Follicle Development and Contribute to the Dermal Sheath and Dermal Papilla Journal of Investigative Dermatology · 2003
    31. Morphological Approach to Hair Disorders Journal of Investigative Dermatology Symposium Proceedings · 2003
    32. Kenogen Dermatology · 2002
    33. Androgenic Alopecia and Stress-Induced Premature Senescence by Cumulative Ultraviolet Light Exposure Exogenous Dermatology · 2002
    34. In Vitro Main Pathways of Steroid Action in Cultured Hair Follicle Cells: Vascular Approach Journal of Investigative Dermatology Symposium Proceedings · 1999
    35. The Biology of Hair Follicles The New England Journal of Medicine · 1999
    36. Diagnostic and Predictive Value of Horizontal Sections of Scalp Biopsy Specimens in Male Pattern Androgenetic Alopecia Journal of The American Academy of Dermatology · 1993
    37. Dynamic Ultrastructural Changes of the Connective Tissue Sheath of Human Hair Follicles During the Hair Cycle Archives of Dermatological Research · 1990
    38. The Comparative Histopathology of Male-Pattern Baldness and Senescent Baldness Clinics in Dermatology · 1988

    Related research 8

    1. Possible Cellular Communication with Human Follicle Dermal Papilla Cells via Secretions from Human Hair Follicle Keratinocytes Journal of St. Marianna University · 2022
    2. Multifaceted Role of Hair Follicle Dermal Cells in Bioengineered Skins British journal of dermatology/British journal of dermatology, Supplement · 2016
    3. A Model System to Analyze the Ability of Human Keratinocytes to Form Hair Follicles Experimental Dermatology · 2014
    4. Review of Hair Follicle Dermal Cells Journal of Dermatological Science · 2009
    5. Versican Expression by Dermal Papilla-Regenerated Hair Follicles: A Promising Tool for Hair-Regrowth Products International Journal of Cosmetic Science · 2004
    6. Study on Hair Follicle Formation Induced by Dermal Papilla Cells Chinese Journal of Reparative and Reconstructive Surgery · 2003
    7. Trans-Species Hair Growth Induction by Human Hair Follicle Dermal Papillae Experimental Dermatology · 2001
    8. Role of Hair Papilla Cells in Induction and Regeneration Processes of Hair Follicles Wound Repair and Regeneration · 1998