In Vitro Main Pathways of Steroid Action in Cultured Hair Follicle Cells: Vascular Approach
December 1999
in “
Journal of Investigative Dermatology Symposium Proceedings
”
steroids angiogenic responses hair follicle cells steroid receptors steroidal enzymes vascular endothelial growth factor VEGF dermal papilla cells DPC androgen receptors estrogen receptors type I 5α-reductase type II 5α-reductase 5α-reductase inhibitor cytochrome-p-450-aromatase androgen receptor antagonist 17ß-estradiol estrogenic pathway VEGF DPC androgen receptors estrogen receptors 5α-reductase inhibitor aromatase androgen receptor antagonist estradiol
Studysummary This study found that in vitro treatments with 5alpha-reductase inhibitors and androgen receptor antagonists strongly stimulate VEGF expression in dermal papilla cells.
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