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      learn Neem Oil

      natural substance from Neem tree with medicinal and pesticidal properties

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      a novel topical treatment that inhibits DHT on androgen receptors

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      a synthetic cortisol used for anti-inflammatory effects

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      community Painkillers May Block Minoxidil

      in Research/Science  12 upvotes 2 weeks ago
      Painkillers like Aspirin may reduce Minoxidil's effectiveness by inhibiting the enzyme PGHS-1, which is crucial for hair growth. Using NSAIDs that inhibit COX-2 or combining Minoxidil with PGF2/E2 analogues or retinoids may enhance its efficacy.

      community Methods Of Staying Safe On Ru58841 - My 2 Cents

      in Research/Science  14 upvotes 2 months ago
      RU58841 is used topically to prevent hair loss by blocking DHT, with suggestions to drink grapefruit juice, take breaks, avoid microneedling, and use lower concentrations to reduce side effects. Users discuss applying it at night to minimize systemic absorption.

      community Is this broscience? From More Plates, More Dates

      in Research/Science  21 upvotes 1 year ago
      The conversation discusses whether finasteride's reduction of DHT and increase in scalp testosterone contribute to hair follicle miniaturization. Some participants argue testosterone does not cause miniaturization, while others suggest that even with reduced DHT, other androgens like testosterone may still contribute to hair loss.

      community Finasteride gyno experience and in dire need of advice

      in Finasteride/Dutasteride  7 upvotes 4 years ago
      A user experienced puffy nipples and lumps from finasteride, leading to a dilemma between continuing treatment with potential surgery or accepting hair loss. They restarted finasteride at a lower dose with supplements but still face side effects and are seeking advice on whether to persist or stop.