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3 / 3 resultslearn Clascoterone
a novel topical treatment that inhibits DHT on androgen receptors
learn Hydrocortisone
a synthetic cortisol used for anti-inflammatory effects
Research
5 / 1000+ resultsresearch In Vitro Main Pathways of Steroid Action in Cultured Hair Follicle Cells: Vascular Approach
Steroids, particularly estrogens and 5α-reductase inhibitors, affect blood vessel-related hair growth processes in hair follicle cells.
research Steroidal 5α-Reductase and 17α-Hydroxylase/17,20-Lyase (CYP17) Inhibitors Useful in the Treatment of Prostatic Diseases
Certain drugs that block specific enzymes can help treat prostate diseases.
research Generation of Comparative Pharmacophoric Model for Steroidal 5α-Reductase I and II Inhibitors: A 3D-QSAR Study on 6-Azasteroids
The study created a model to help design new inhibitors for steroidal 5α-reductase enzymes.
research Effect of Carbamates on mRNA Encoding Lipid Enzymes in Hamster Flank Organs
Carbamates may help treat androgen-dependent conditions by changing how certain lipid enzymes are produced.
research New 5α-Reductase Inhibitors: In Vitro and In Vivo Effects
Four new compounds were more effective than finasteride in treating prostate issues and hair loss, with one being 100 times more active and safe for use.
Community Join
5 / 533 resultscommunity Severe dry eye: finasteride vs dutasteride
Woman uses antiandrogens for hair thinning prevention, experiences severe dry eye with finasteride. Asks if dutasteride could be better despite potential for worse dry eye.
community Is this broscience? From More Plates, More Dates
The conversation discusses whether finasteride's reduction of DHT and increase in scalp testosterone contribute to hair follicle miniaturization. Some participants argue testosterone does not cause miniaturization, while others suggest that even with reduced DHT, other androgens like testosterone may still contribute to hair loss.
community Finasteride gyno experience and in dire need of advice
A user experienced puffy nipples and lumps from finasteride, leading to a dilemma between continuing treatment with potential surgery or accepting hair loss. They restarted finasteride at a lower dose with supplements but still face side effects and are seeking advice on whether to persist or stop.
community Everyone is ignoring that plasma finasteride levels are 100x lower with topical compared to oral.
Topical finasteride results in plasma levels 100 times lower than oral finasteride, potentially reducing systemic side effects. Users report similar efficacy with fewer side effects, suggesting a preference for topical application.
community What Works to Restore Hairloss for Cis-Males? Not Much
Hair regrowth treatments for cis-males include Minoxidil, Finasteride, and RU58841. Estrogen and testosterone blockers can help restore hair loss but may not suit everyone.