What Ages Hair?

February 2017 in “ International Journal of Women's Dermatology ”

Assaf Monselise, David Cohen, Rita Wanser, Jerry Shapiro

pattern hair loss dihydrotestosterone senescent alopecia minoxidil androgenetic alopecia hair fiber damage anti-inflammatory effects male-pattern baldness age-related thinning scalp health UV protection PHL DHT AGA Rogaine

Studysummary This source summarizes discussions by an advisory board of twelve experts on hair loss, focusing on heredity, aging, and environmental impacts, and emphasizing strategies that may slow alopecia.

Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer

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Research cited in this study

26 / 26 results

Efficacy, Safety, and Tolerability of Dutasteride 0.5 mg Once Daily in Male Patients with Male Pattern Hair Loss: A Randomized, Double-Blind, Placebo-Controlled, Phase III Study

research Efficacy, Safety, and Tolerability of Dutasteride 0.5 mg Once Daily in Male Patients with Male Pattern Hair Loss: A Randomized, Double-Blind, Placebo-Controlled, Phase III Study

92 citations , June 2010 in “Journal of The American Academy of Dermatology”

This study found that 0.5 mg of dutasteride significantly improved hair growth compared to placebo and was well tolerated over six months in men with male pattern hair loss.

research Ceramic Flat Irons: Improper Use Leading to Acquired Trichorrhexis Nodosa

34 citations , December 2009 in “Journal of the American Academy of Dermatology”

This review discusses the use of ceramic-coated flat irons for hair straightening and reports no clinical results; the authors highlight potential hair damage risks from improper use.

A Multicenter, Randomized, Placebo-Controlled, Double-Blind Clinical Trial of a Novel Formulation of 5% Minoxidil Topical Foam Versus Placebo in the Treatment of Androgenetic Alopecia in Men

research A Multicenter, Randomized, Placebo-Controlled, Double-Blind Clinical Trial of a Novel Formulation of 5% Minoxidil Topical Foam Versus Placebo in the Treatment of Androgenetic Alopecia in Men

142 citations , August 2007 in “Journal of The American Academy of Dermatology”

This study found that a new 5% minoxidil foam formulation significantly increased hair counts and improved hair loss condition in men with androgenetic alopecia over 16 weeks compared to placebo.

research The Effect of Tripeptide-Copper Complex on Human Hair Growth In Vitro

39 citations , July 2007 in “Archives of Pharmacal Research”

A tripeptide-copper complex may help hair grow by increasing cell growth and decreasing cell death.

research Dutasteride Improves Male Pattern Hair Loss in a Randomized Study in Identical Twins

39 citations , March 2007 in “Journal of Cosmetic Dermatology”

This study in identical twin males with androgenetic alopecia found that dutasteride significantly improved hair growth compared to placebo over one year.

The Importance of Dual 5α-Reductase Inhibition in the Treatment of Male Pattern Hair Loss: Results of a Randomized Placebo-Controlled Study of Dutasteride Versus Finasteride

research The Importance of Dual 5α-Reductase Inhibition in the Treatment of Male Pattern Hair Loss: Results of a Randomized Placebo-Controlled Study of Dutasteride Versus Finasteride

215 citations , November 2006 in “Journal of The American Academy of Dermatology”

This study found that dutasteride increased scalp hair growth in men with male pattern hair loss, particularly at a 2.5 mg dose, and was more effective than finasteride over 24 weeks.

research Reversal of Androgenetic Alopecia by Topical Ketoconazole: Relevance of Anti-Androgenic Activity

38 citations , September 2006 in “Journal of Dermatological Science”

This study evaluated the effect of 2% ketoconazole lotion for androgenetic alopecia, but the results regarding its effectiveness on clinical appearance remained unclear.

research Changes in Hair Weight in Men with Androgenetic Alopecia After Treatment with Finasteride (1 mg Daily): Three- and Four-Year Results

66 citations , June 2006 in “Journal of The American Academy of Dermatology”

This study found that long-term finasteride treatment in men with androgenetic alopecia significantly increased hair weight and count compared to placebo over nearly four years.

research Finasteride Treatment of Female Pattern Hair Loss

108 citations , March 2006 in “Archives of Dermatology”

This study observed that 62% of premenopausal women with female pattern hair loss reported improvement when treated with oral finasteride and an oral contraceptive containing drospirenone and ethinyl estradiol.

research Female Pattern Hair Loss, Sebum Excretion, and the End-Organ Response to Androgens

31 citations , October 2005 in “British Journal of Dermatology”

This study found that sebum excretion is not increased in women with female pattern hair loss, suggesting nonandrogenic factors may contribute to hair loss in some women without hirsutism.

Novel and Established Potassium Channel Openers Stimulate Hair Growth In Vitro: Implications for Their Modes of Action in Hair Follicles

research Novel and Established Potassium Channel Openers Stimulate Hair Growth In Vitro: Implications for Their Modes of Action in Hair Follicles

35 citations , March 2005 in “Journal of Investigative Dermatology”

In this in vitro study, minoxidil, diazoxide, and the novel compound NNC 55-0118 increased hair follicle growth, supporting deer follicles as a viable bioassay for ATP-sensitive potassium channel modulators.

research Safety of Topical Minoxidil Solution: A One-Year, Prospective, Observational Study

26 citations , July 2003 in “Journal of Cutaneous Medicine and Surgery”

This study found that topical minoxidil solution is a safe treatment for androgenetic alopecia, with no increase in cardiovascular events or adverse pregnancy outcomes observed.

research Androgenetic Alopecia in Women

139 citations , June 2003 in “Journal of Investigative Dermatology Symposium Proceedings”

This article reviews androgenetic alopecia in women, highlighting diagnosis criteria and noting that topical minoxidil is currently the only proven treatment for hair growth; it reports no clinical trial findings.

research Hair Loss and Hirsutism in the Elderly

22 citations , February 2002 in “Clinics in Geriatric Medicine”

This review discusses the biology of hair follicles and common hair disorders in the elderly but reports no new clinical results.

research Allergic Contact Dermatitis to Topical Minoxidil Solution: Etiology and Treatment

123 citations , February 2002 in “Journal of The American Academy of Dermatology”

Minoxidil can cause skin allergy; use alternative solvents or treatments if allergic.

research Possible Mechanisms of Miniaturization During Androgenetic Alopecia or Pattern Hair Loss

116 citations , September 2001 in “Journal of The American Academy of Dermatology”

This study suggests that miniaturization in pattern hair loss may occur abruptly and can be reversed with treatment, as supported by histologic evidence in finasteride-responsive patients.

Measuring Reversal of Hair Miniaturization in Androgenetic Alopecia by Follicular Counts in Horizontal Sections of Serial Scalp Biopsies: Results of Finasteride 1mg Treatment of Men and Postmenopausal Women

research Measuring Reversal of Hair Miniaturization in Androgenetic Alopecia by Follicular Counts in Horizontal Sections of Serial Scalp Biopsies: Results of Finasteride 1mg Treatment of Men and Postmenopausal Women

145 citations , December 1999 in “Journal of Investigative Dermatology Symposium Proceedings”

Finasteride 1mg helps reverse hair miniaturization in men and postmenopausal women.

Changes in Hair Weight and Hair Count in Men with Androgenetic Alopecia After Application of 5% and 2% Topical Minoxidil, Placebo, or No Treatment

research Changes in Hair Weight and Hair Count in Men with Androgenetic Alopecia After Application of 5% and 2% Topical Minoxidil, Placebo, or No Treatment

115 citations , November 1999 in “Journal of The American Academy of Dermatology”

In this study, men using 2% and 5% minoxidil solutions experienced a significant increase in hair weight for 96 weeks compared to placebo, with effects diminishing after treatment cessation.

research The Midline Part: An Important Physical Clue to the Clinical Diagnosis of Androgenetic Alopecia in Women

90 citations , January 1999 in “Journal of The American Academy of Dermatology”

This article highlights a specific, yet largely unrecognized, sign that aids in diagnosing androgenetic alopecia in women, emphasizing its practical application in clinical settings.

research Ketoconazole Shampoo: Effect of Long-Term Use in Androgenic Alopecia

92 citations , January 1998 in “Dermatology”

This study found that 2% ketoconazole shampoo improved hair density and anagen follicle proportion in androgenic alopecia similarly to minoxidil treatment, suggesting a potential role for Malassezia in inflammation.

Activation of Cytoprotective Prostaglandin Synthase-1 by Minoxidil as a Possible Explanation for Its Hair Growth-Stimulating Effect

research Activation of Cytoprotective Prostaglandin Synthase-1 by Minoxidil as a Possible Explanation for Its Hair Growth-Stimulating Effect

81 citations , February 1997 in “Journal of Investigative Dermatology”

This study suggests that minoxidil activates PGHS-1, which may explain its hair growth-stimulating effects and could aid in designing more potent hair growth-promoting drugs.

research Diagnostic and Predictive Value of Horizontal Sections of Scalp Biopsy Specimens in Male Pattern Androgenetic Alopecia

309 citations , May 1993 in “Journal of The American Academy of Dermatology”

This study concluded that horizontal sections of scalp biopsy specimens provide more diagnostic information for male pattern androgenetic alopecia than vertical sections and can predict hair regrowth potential following topical minoxidil therapy.

research Direct T-Cell Effects of Minoxidil

7 citations , October 1988 in “Clinics in Dermatology”

Minoxidil may help hair regrowth in alopecia areata by affecting T-cells.

research The Comparative Histopathology of Male-Pattern Baldness and Senescent Baldness

143 citations , October 1988 in “Clinics in Dermatology”

This review discusses the histopathology of male-pattern baldness and highlights ongoing disputes over several aspects, including sebaceous gland size and follicle loss, reporting no new clinical findings.

research The Hair Cycle And Its Regulation

38 citations , October 1988 in “Clinics in Dermatology”

This article reviews the historical development of understanding the hair growth cycle, particularly anagen, catagen, and telogen phases, and reports no new clinical findings.

research Immunohistochemical Characterization of the Cellular Infiltrate in Severe Alopecia Areata Before and After Minoxidil Treatment

31 citations , January 1987 in “Dermatology”

This study reports that topical minoxidil led to normalization of hair follicle characteristics in 36 of 47 severe alopecia areata patients, and indicated a shift in T cell populations, suggesting potential immunomodulatory effects.