Safety and Efficacy of ALRV5XR in Women with Androgenetic Alopecia or Telogen Effluvium: A Randomised, Double-Blinded, Placebo-Controlled Clinical Trial

June 2021 in “ EClinicalMedicine ”

Peter D. Feldman, Klaus M. Fiebig, Charles Piwko, Boris M. Mints, Dennis Brown, Deborah J. Cahan, Jaime Guevara-Aguirre

ALRV5XR androgenetic alopecia telogen effluvium terminal hair density placebo-controlled trial standard therapies female hair loss AGA TE

Studysummary In this study, ALRV5XR significantly increased hair regrowth in women with androgenetic alopecia or telogen effluvium, with no adverse events reported. Our plain-language summary of this paper — not a Tressless recommendation.

The study evaluated the safety and efficacy of ALRV5XR in women with androgenetic alopecia (AGA) or telogen effluvium (TE) through a 24-week randomized, double-blind, placebo-controlled trial involving 46 participants. Results showed significant improvements in terminal hair density, with increases ranging from 30.1 to 33.9 hairs/cm² in the ALRV5XR group compared to placebo. The treatment had a high response rate (66.7%) and was well-tolerated with no severe adverse events reported. ALRV5XR demonstrated superior efficacy over standard therapies, suggesting its potential as a new standard of care for female hair loss.

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