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research Age-Related Changes in Female Scalp Dermal Sheath and Dermal Fibroblasts: How the Hair Follicle Environment Impacts Hair Aging

14 citations , December 2020 in “Journal of Investigative Dermatology”

This study observed that aging leads to significant structural and biological changes in the scalp's hair follicle environment in women, which may affect hair growth.

research Reflectance confocal miscroscopy and dermoscopy analysis of a case of connective tissue nevi

June 2018 in “Chinese Journal of Dermatology”

This study reported that connective tissue nevi show distinctive dermoscopic and RCM features, with RCM being particularly helpful for diagnosing lesions of less than one year in duration.

research Fibroblast heterogeneity: implications for human disease

299 citations , January 2018 in “Journal of Clinical Investigation”

This review explores fibroblast heterogeneity in the mammalian dermis and suggests potential therapeutic applications by targeting fibroblast subtypes, but reports no new experimental results.

research Dermal fibroblast in cutaneous development and healing

115 citations , December 2017 in “Wiley Interdisciplinary Reviews-Developmental Biology”

This review discusses the origins, differentiation, and function of dermal fibroblasts in skin development and healing, reporting no new clinical results.

research Tp63-expressing adult epithelial stem cells cross lineages boundaries revealing latent hairy skin competence

8 citations , November 2020 in “Nature Communications”

This study demonstrates that Tp63-expressing epithelial stem cells from non-skin tissues can respond to skin morphogenetic signals and contribute to the formation of hair follicles, sebaceous glands, and epidermis.

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community Everything you ever wanted to know about Pelage Pharma's PP405: how it works and what to expect

126 upvotes 3 months ago

PP405 may encourage earlier hair growth and slightly increase visible hair count but does not reverse hair follicle miniaturization in male pattern baldness. It does not address damage to the dermal papilla or broken Wnt signaling.

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