Anatomy and Physiology of Hair

May 2017 in “ InTech eBooks ”

Bilgen Erdoğan

Studysummary This chapter reviews the anatomy and physiology of hair follicles but reports no new research findings or clinical results. Our plain-language summary of this paper — not a Tressless recommendation.

The document "Anatomy and Physiology of Hair" provided a comprehensive overview of hair structure and function, emphasizing its protective, thermoregulatory, and social roles. It detailed the hair growth cycle, including anagen (growth), catagen (regression), telogen (rest), and exogen (shedding) phases, influenced by factors like age and nutrition. The development of hair follicles involved complex interactions between epithelial and mesenchymal cells, regulated by genes and signaling pathways such as WNT, EDA/EDAR, and BMP. The document also covered the classification of hair into vellus and terminal types, the structure of the hair shaft and follicle, and the role of melanocytes in hair pigmentation. Understanding these processes was deemed essential for addressing hair disorders.

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research The Human Hair: From Anatomy to Physiology

107 citations , December 2013 in “International Journal of Dermatology”

This review summarizes the anatomical and physiological aspects of human hair and its clinical significance, but does not report new research findings.

research Human Hair Follicle: Reservoir Function and Selective Targeting

97 citations , September 2011 in “British Journal of Dermatology”

The human hair follicle can store topical compounds and be targeted for drug delivery with minimal side effects.

research Hair Follicle as a Target of Stress Hormones and Autoimmune Reactions

61 citations , September 2010 in “Journal of Dermatological Science”

This review discusses the interplay between hormonal and immune systems in hair follicles and reports no new results, highlighting the need for further research on their role in skin biology and alopecia areata.

research The Hair Follicle as a Dynamic Mini-Organ

759 citations , February 2009 in “Current Biology”

This review summarizes fundamental concepts and recent advancements in hair follicle biology, including insights from mouse models into broader molecular and cellular processes relevant to regeneration and development.

research The Biology of Hair Growth

10 citations , January 2009 in “Elsevier eBooks”

This review discusses the structure, functions, and growth cycle of human hair, emphasizing its reduced growth and protective roles, and reports no new research findings.

research Shape Variability and Classification of Human Hair: A Worldwide Approach

95 citations , January 2007 in “Human biology”

This study proposes a new, objective method to classify human hair into eight categories based on specific shape measurements, rather than traditional ethnicity-based classifications.

research Biology of the Hair Follicle: The Basics

224 citations , March 2006 in “Seminars in Cutaneous Medicine and Surgery”

This article discusses the hair follicle's regenerative cycles and the molecular mechanisms influencing them, emphasizing the need for therapeutic targeting of the "hair cycle clock" to manage hair growth disorders, without reporting new research findings.

research Human Hair Keratin-Associated Proteins

226 citations , January 2006 in “International review of cytology”

Keratin-associated proteins are crucial for hair strength and structure.

research Hair Follicle Pigmentation: Mechanisms and Factors Influencing Melanin Production

450 citations , January 2005 in “The journal of investigative dermatology/Journal of investigative dermatology”

This article reviews follicular melanogenesis, detailing how melanin synthesis and its regulation in hair follicles depend on a complex interplay of cellular and molecular mechanisms, but reports no new clinical findings.

research Hair Follicle Differentiation And Regulation

199 citations , January 2004 in “The International Journal of Developmental Biology”

This review discusses advances in understanding hair and hair follicle structure, gene expression, and molecular signals in hair formation, without reporting new clinical findings.

research Variations of Hair Follicle Size and Distribution in Different Body Sites

405 citations , January 2004 in “Journal of Investigative Dermatology”

This study found that hair follicle characteristics vary significantly across different body sites, with the forehead and calf showing the highest potential follicular reservoirs, challenging previous assumptions about skin appendage distribution.

research Human Hair: A Unique Physicochemical Composite

203 citations , June 2003 in “Journal of the American Academy of Dermatology”

This article reviews the structure and chemistry of hair across ethnicities and how these factors affect hair properties and treatment responses, but reports no new research findings.

research Molecular Mechanisms Regulating Hair Follicle Development

854 citations , February 2002 in “The journal of investigative dermatology/Journal of investigative dermatology”

This review summarizes recent advances in understanding the molecular mechanisms of hair follicle formation and discusses potential future clinical applications for treating hair loss and skin tumors, but it reports no new clinical results.

research Hair Structure Anatomy And Comparative Anatomy Dedicated To The Memory Of The Late Dr. R. E. Rivett Whose Untimely Death Prevented His Role In Co-Authorship

50 citations , March 2001 in “Clinics in dermatology”

This paper reviews the complex anatomy and development of human hair and emphasizes the need to understand these processes for interpreting drug incorporation into hair, with no new clinical results reported.

research Morphogenesis and Renewal of Hair Follicles from Adult Multipotent Stem Cells

949 citations , January 2001 in “Cell”

This study demonstrated that multipotent stem cells in adult mice whisker follicles migrate to produce whisker growth, and that this process requires precise control of stem cell trafficking.

research The Biology of Hair Follicles

1113 citations , August 1999 in “The New England Journal of Medicine”

This article discusses the biologic and psychosocial significance of hair, the current limitations in hair growth drugs, and anticipates future therapies based on advancing hair follicle research.

research What Controls Hair Follicle Cycling?

50 citations , August 1999 in “Experimental dermatology”

This review discusses the need for more research on how the chronobiological control systems regulate hair follicle cycling and reports no new results.

research Principles of Hair Cycle Control

109 citations , December 1998 in “The Journal of Dermatology”

This review discusses the hair follicle cycle's complex regulation and highlights the potential for targeting catagen control in future therapies without presenting new experimental data.

research Dermal-Epidermal Interactions in Hair Follicle Development and Maintenance

114 citations , October 1996 in “Dermatologic clinics”

This chapter reviews laboratory models used for studying alopecia therapies but provides no new experimental findings.

research Growth Factors in Hair Organ Development and the Hair Growth Cycle

90 citations , October 1996 in “Dermatologic Clinics”

This study found that red ginseng oil may enhance hair growth and protect skin from UV damage in mouse models by promoting regenerative processes and reducing inflammation.

research Hair Follicle Companion Layer: Reacquainting an Old Friend

55 citations , May 1995 in “The journal of investigative dermatology/Journal of investigative dermatology”

research The Secret Life of the Hair Follicle

745 citations , February 1992 in “Trends in genetics”

This article describes the potential role of various growth factors and molecules in regulating mammalian hair follicle development but does not present new experimental results.

research Hair Anatomy for the Clinician

139 citations , July 1991 in “Journal of The American Academy of Dermatology”

This article discusses the structure of hair follicles and their significance in evaluating hair disorders, but it does not report any new research findings.