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      community PP405 mechanism question - looking for discussion

       7 upvotes 5 months ago
      PP405 may promote short-term hair growth by pushing follicles into the growth phase, but concerns exist about long-term effects due to lack of rest phases. Users discuss various treatments like finasteride, minoxidil, spironolactone, alfatradiol, and investigational drugs like KX-826 and GT20029 for hair maintenance and regrowth.

      community Third shedding phase on less than 6 months of treatment

      in Chat  7 upvotes 4 months ago
      The user has been using minoxidil for almost 6 months and finasteride for almost 4 months, experiencing significant shedding and minimal stabilization. They are considering switching to dutasteride if no improvements are seen and are advised to be patient, as results may take up to 2 years.

      community PYRILUTAMIDE PHASE 3 RESULTS : No statistical significance

       124 upvotes 2 years ago
      The phase 3 trial results for Pyrilutamide showed no significant difference from the control treatment in increasing hair count, leading to the company halting its development. Users discussed their disappointment and skepticism about hair loss treatments, with some mentioning other treatments like Minoxidil, Finasteride, and RU58841.

      community Pp405 phase 2a clinical results

       37 upvotes 1 year ago
      PP405 shows initial promise for treating androgenetic alopecia, with safety confirmed in early trials, but skepticism remains due to limited data. Further trials are needed to determine its true efficacy and potential market impact.

    Research

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      The Hair Cycle

      research The hair cycle

      375 citations , February 2006 in “Journal of Cell Science”
      This article reviews the stages and regulation of the hair cycle, highlighting molecular regulators involved, but it does not present new research findings.
      The Hair Cycle

      research The hair cycle

      103 citations , January 2006 in “Journal of Cell Science”
      This review summarizes the major events and regulators of the hair cycle in mammals but reports no new experimental results; it emphasizes the complex regulation of stem cell activation and differentiation during hair growth.

      research Anatomy and Physiology of Hair

      14 citations , May 2017 in “InTech eBooks”
      This chapter reviews the anatomy and physiology of hair follicles but reports no new research findings or clinical results.

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