Studysummary This review explores the structure and development of the hair cuticle, highlighting difficulties in studying some aspects and proposing new experimental approaches, but reports no new clinical results. Our plain-language summary of this paper — not a Tressless recommendation.
The review from May 2019 discussed the structure and function of the hair cuticle, emphasizing its protective role for the inner cortex. It detailed the three layers of the cuticle—A-layer, exocuticle, and endocuticle—and their distinct properties, including high disulphide crosslinking for toughness and the hydrophobic nature due to 18-methyleicosanoic acid (18-MEA). Despite extensive research, some aspects of cuticle structure and development remained unclear, highlighting the need for innovative techniques like TEM autoradiography to study these areas. The review underscored the importance of further research to improve understanding and treatment of hair.
11 citations
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May 2013 in “Journal of Investigative Dermatology” KRTAP10 proteins help form the hair shaft's tough outer layer by interacting with specific hair keratins.
34 citations
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September 2007 in “Experimental Dermatology” This study found that the outer protein layer of Merino wool is rich in sulfur-containing proteins similar to those found in both sheep wool and human hair.
30 citations
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January 1994 in “Micron” This study found that the formation of the fibre cuticle surface in Merino sheep is similar to the epidermal stratum corneum process and not from a modified plasma membrane as previously thought.
90 citations
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January 1979 in “International review of cytology” This chapter reviews the complexity of hair and wool follicle formation, emphasizing the importance of cytological studies to understand the relationship between cellular components.
138 citations
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November 1977 in “Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics” 82 citations
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November 1959 in “Annals of the New York Academy of Sciences” This article reviews recent findings on enzymes and proteins in hair follicles and reports no new experimental results.
191 citations
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November 1959 in “Annals of the New York Academy of Sciences” This article reports electron microscope studies on the structure of hair and wool, but it does not present new clinical findings.
34 citations
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July 1958 in “Biochimica et Biophysica Acta”
