Metabolomic Analysis of Amino Acids and Lipids in Human Hair Altered by Dyeing, Perming, and Bleaching

    April 2016 in “ Experimental Dermatology ”
    Kyung‐Mi Joo, A Young Kim, Su‐Na Kim, Boo‐Min Kim, Hae Kwang Lee, SeungJin Bae, J. H. Lee, Kyung‐Min Lim
    TLDR Chemical treatments like dyeing, perming, and bleaching damage hair by altering amino acids and lipids.
    The study investigated the effects of chemical treatments like dyeing, perming, and bleaching on the amino acids and lipids in human hair. Using metabolomic analysis, significant alterations in amino acids such as cysteic acid (Cya), tryptophan (Trp), and methionine (Met) were observed, indicating hair damage. The study found that Cya levels increased with chemical treatments, serving as a marker for damage, while Met and Trp levels decreased. Lipids, including free fatty acids (FFAs) and 18-methyl eicosanoic acid (18-MEA), were also depleted, correlating with the severity of hair damage. The research highlighted the potential of using these biochemical changes as biomarkers for assessing hair damage and developing safer hair care products.
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