Beyond the Follicle: A Narrative Review on How Systemic Diseases and Drugs Affect Alopecia

Microneedles improve drug delivery for skin diseases, enhancing treatment effectiveness and patient compliance.

Current treatments for androgenetic alopecia are complex and promising, but more research is needed.

Understanding hair growth pathways can lead to better hair loss treatments.

Psoriatic alopecia is a challenging hair loss condition linked to psoriasis, needing better diagnosis and personalized treatments.

JAK inhibitors effectively and safely treat alopecia areata with few serious side effects.

Accurate diagnosis is crucial to distinguish between allergy and irritation from topical minoxidil.

Androgenetic alopecia starts earlier in males than females, with different treatments, and is linked to income, education, alcohol use, and mental health.

Combining specific proteins and cell-derived particles may help treat hair loss.

Low iron levels may be linked to hair loss in women.

Docetaxel often causes hair loss, with limited effective treatments and no cure for permanent hair loss.

Injectable treatments can effectively and safely improve hair growth in adults with androgenetic alopecia.

Antioxidant-rich diets may reduce hair loss risk, while pro-inflammatory diets may increase it, especially in women.

Problems with arginine processing in hair follicles might contribute to common hair loss, and arginine supplements could help treat it.

Hair aging is caused by stress, hormones, inflammation, and DNA damage affecting hair growth and color.

Saw palmetto extract reduced hair loss and improved hair growth in people with hair thinning.

Cetosomal minoxidil is safer and as effective as alcohol-based minoxidil for male hair loss treatment.

QR678 Neo® improved seborrheic dermatitis symptoms in a small group of patients.

Using adipose-derived stem cell media with minoxidil may help regrow hair in men with hair loss.

Thyroid problems can cause hair loss and change hair texture.

Two drugs, finasteride and minoxidil, are approved for hair loss treatment, but new therapies are being developed.

Garlic can help hair grow by activating certain growth pathways, and it works whether you eat it or apply it to your scalp.

Skin side effects from CDK4/6 inhibitors in breast cancer patients are generally mild and treatable, allowing most patients to continue treatment.

The conclusion suggests that focusing on certain cellular pathways may improve the prevention and repair of hair loss caused by radiotherapy.

Scalp cooling is the only FDA-approved method to prevent hair loss from chemotherapy, but other treatments like minoxidil and PRP are being tested.

Using both minoxidil and finasteride together is more effective for male hair loss than using either one alone.

Immune checkpoint inhibitors can cause skin issues but are linked to better cancer outcomes.

Melatonin may help improve hair growth in people with certain types of hair loss.

A holistic approach is needed to effectively address hair loss by understanding and influencing the hair growth cycle.

A woman's hair grew back after treatment for a rare hair loss caused by proton therapy.

PRP might help with hair growth, but the evidence is weak.

People with alopecia have a higher risk of thyroid cancer.

Natural products may help treat hair loss by promoting hair growth with fewer side effects.

cp-asiAR may effectively treat androgenetic alopecia by promoting hair growth and reducing androgen receptor activity.

Female pattern hair loss is common in women with polycystic ovarian syndrome.

Hair growth and health are influenced by factors like age, environment, and nutrition, and are controlled by various molecular pathways. Red light can promote hair growth, and understanding these processes can help treat hair-related diseases.

Some COVID-19 patients lose hair, with the most common type linked to male hormones and possibly increasing the risk of severe illness.

QR678 Neo® is a safe and effective treatment for hair loss in men and women.

QR678 Neo® hair growth treatment is effective for hair loss caused by Covid-19.

QR678 and QR678 Neo treatments, combined with corticosteroid injections, work better for alopecia areata than corticosteroid injections alone.

Tofacitinib successfully treated hair loss in a Crohn's disease patient who previously used adalimumab.

Topical finasteride is an effective and safer treatment for male hair loss.

Different types of persistent hair loss after chemotherapy respond differently to treatments.

Alopecia areata patients, especially women with nail issues or atopic diseases, are at higher risk for other autoimmune diseases.

Combination therapy with QR 678 Neo and 5% Minoxidil is most effective for male hair loss.

Intradermal injections improve hair density and thickness better, while derma roller is more convenient.

The document concludes that we need more research to understand Telogen Effluvium and find effective treatments.

Trichoscopy is useful for correctly diagnosing tinea capitis in adults with unexplained hair loss.

QR 678 and QR678 Neo treatments are effective for hair loss in women with PCOS.

QR 678 and QR 678 Neo are safe and promote hair growth, potentially helping chemotherapy-induced hair loss.

Activating the Wnt/β-catenin pathway could lead to new hair loss treatments.

The conclusion is that treatments for Telogen Effluvium exist, but standard treatment guidelines are needed.

Clascoterone may be a promising treatment for hair loss.

QR678 treatments were more effective and comfortable for male hair loss than PRP treatments.

Botulinum toxin injections may help treat hair loss by blocking harmful secretion in hair follicles.

Anticoagulant therapy may cause hair loss, especially in women, and stopping the medication can lead to hair regrowth.

Certain diets may help with hair growth in people with different types of hair loss.

Post-finasteride syndrome causes lasting sexual, neurological, and physical side effects in some people after taking finasteride.

Type 2 diabetes may increase the risk of severe hair loss in African American women.

Valproic acid increases the risk of hair loss more than other drugs, especially in migraine patients, and lamotrigine may be a safer alternative.

Methotrexate treatment often causes hair loss.

Indian dermatologists recommend treating common hair loss with a balanced diet, stress reduction, mild shampoos, and sometimes minoxidil and supplements.

Alopecia areata is an autoimmune disease causing patchy hair loss, often with other autoimmune disorders, but its exact causes are unknown.

Some vitamins and minerals like vitamin D and iron can help with certain types of hair loss, but more research is needed for others.

Dupilumab may cause significant hair loss, which can reverse after stopping the drug.

Dermal Papilla cells are a promising tool for evaluating hair growth treatments.

Some psychiatric drugs can cause severe hair loss, especially valproic acid, and it's more likely in women or those with thyroid issues or past hair loss.

Stem cells, especially from fat tissue and Wharton's jelly, can potentially regenerate hair follicles and treat hair loss, but more research is needed to perfect the treatment.

Some birth control pills can cause hair loss, and switching to ones with less androgen should help.

A man with complete hair loss and ulcerative colitis regrew hair after treatment with azathioprine.

Some blood thinners can cause hair loss, but switching medications can stop it.

Minoxidil, finasteride, and low-level laser light therapy effectively treat hair loss.

Male pattern baldness involves genetics, hormones, and needs better treatments.

Alopecia areata patients often have eczema, thyroid issues, vitamin-D deficiency, and anemia.

Hair loss led to the diagnosis of Cushing's disease in a patient, showing that hair loss can be a sign of hormonal disorders.

Correcting nutrient deficiencies may help with hair loss, but the benefits of supplements without a deficiency are uncertain and could be harmful.

Most Indian people with hair loss in the study lacked nutrients, especially iron.

Caffeine-based liquid 0.2% is as effective as minoxidil 5% for treating male hair loss.

5-alpha reductase inhibitors are generally safe but can cause sexual side effects and require patient education on risks.

Some new oral anticoagulants may also cause hair loss and might not be better than traditional ones for preventing hair loss.

Rosemary oil and minoxidil 2% both effectively increase hair count in people with androgenetic alopecia, but rosemary oil causes less scalp itching.

Sertraline can cause hair loss, which stops after stopping the drug.

PRP injections may improve hair thickness and density in female hair loss patients.

Hair follicle dermal stem cells are key for regenerating parts of the hair follicle and determining hair type.

The conclusion is that proper signaling is crucial for hair growth and development, and errors can lead to cancer or hair loss.

Proteins from stem cells improved hair growth in patients with hair loss.

Eating the right nutrients can improve hair health, but taking extra supplements usually doesn't help unless you have a deficiency.

Selenoproteins are crucial for healthy skin and hair.

Hair loss in men treated best with early medication or transplant, new treatments researched.

Gefitinib can cause slower, finer, brittle, and curly scalp hair.

Keeping radiation doses under 16 Gy may reduce permanent hair loss.

The medication lopinavir-ritonavir may cause severe hair loss.

A tripeptide-copper complex may help hair grow by increasing cell growth and decreasing cell death.

BMP signaling is crucial for skin and hair growth.

Inhibiting Bmp signaling disrupts hair growth and differentiation.

Procyanidin compounds from grape seeds were found to significantly increase mouse hair growth.

Zidovudine may cause hair loss in advanced-stage HIV patients.

Some drugs can cause hair loss or increase hair growth, but these effects are usually reversible when the drug is stopped.