Agent-Specific Effects of Anticoagulant-Induced Alopecia

    Angela C. Weyand, Jordan A. Shavit
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    TLDR Some blood thinners can cause hair loss, but switching medications can stop it.
    In a 2017 case report, a 20-year-old female with type 2 spinal muscular atrophy developed alopecia due to the use of anticoagulants for her recurrent deep vein thrombosis (DVT). She experienced hair loss with both heparin derivatives and new oral anticoagulants, but the condition was reversible after stopping these medications. The patient was able to continue long-term anticoagulation with fondaparinux without further hair loss. This case highlights the need for personalized treatment plans, as alopecia can be a side effect of various anticoagulants and may require several trials to find a suitable medication. The exact causes of anticoagulant-induced alopecia are still unknown, indicating a need for more research to understand whether it is related to dosage or individual patient factors.
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