Traditional Anticoagulants and Hair Loss: A Role for Direct Oral Anticoagulants? A Review of the Literature

    January 2016 in “ Drugs - Real World Outcomes ”
    Magdelana Watras, Jignesh P. Patel, Roopen Arya
    Studysummary This review discusses the potential link between direct oral anticoagulants and hair loss, suggesting DOACs may not be a suitable alternative for patients with alopecia from traditional anticoagulants; however, no clinical results are reported.
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    Research cited in this study 8

    1. Hair Loss Is a Potential Side Effect of Novel Oral Anticoagulants – Findings From the Dresden NOAC Registry (NCT01588119) Blood · 2012
    2. Enoxaparin-Induced Alopecia in Patients with Cerebral Venous Thrombosis Journal of Clinical Pharmacy and Therapeutics · 2006
    3. Diffuse Alopecia in a Hemodialysis Patient Caused by a Low-Molecular-Weight Heparin, Tinzaparin American Journal of Kidney Diseases · 2003
    4. Drug-Associated Alopecia International Journal of Dermatology · 1995
    5. Hair Growth Inhibition by Heparin in Mice: A Model System for Studying the Modulation of Epithelial Cell Growth by Glycosaminoglycans British Journal of Dermatology · 1991
    6. Alopecia: A Pathologist's View International Journal of Dermatology · 1982
    7. Some Chemical Influences on Hair Growth and Pigmentation British Journal of Dermatology · 1965
    8. Inhibition of Keratinizing Structures by Systemic Drugs Pharmacological Reviews · 1963