Garlic Exosomes Promote Hair Growth Through the Wnt/Beta-Catenin Pathway and Growth Factors

    July 2023 in “ Cureus ”
    Esma Yüksel, Demet Cicek, Betül Demir … Merve Yildirim
    Studysummary This study found that garlic exosomes induced hair growth in rats by increasing anagen follicle counts and activating multiple signaling pathways, including Wnt-1, β-catenin, and TGF-β1.
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    Research cited in this study 8

    1. Effects of Adipose-Derived Stem Cells and Platelet-Rich Plasma Exosomes on the Inductivity of Hair Dermal Papilla Cells PubMed · 2021
    2. Dermal Exosomes Containing miR-218-5p Promote Hair Regeneration by Regulating β-Catenin Signaling Science Advances · 2020
    3. Regulation of Hair Follicle Development by Exosomes Derived from Dermal Papilla Cells Biochemical and Biophysical Research Communications · 2018
    4. Genes Influencing Hair Follicle Development Mehmet Akif Ersoy Üniversitesi Veteriner Fakültesi dergisi · 2017
    5. VEGF Induces Proliferation of Human Hair Follicle Dermal Papilla Cells Through VEGFR-2-Mediated Activation of ERK Experimental Cell Research · 2012
    6. Combination of Topical Garlic Gel and Betamethasone Valerate Cream in the Treatment of Localized Alopecia Areata: A Double-Blind Randomized Controlled Study Indian Journal of Dermatology Venereology and Leprology · 2007
    7. Effect of 1 mg/Day Finasteride on Concentrations of Serum Prostate-Specific Antigen in Men With Androgenic Alopecia: A Randomized Controlled Trial Lancet Oncology · 2006
    8. Identification of Androgen-Inducible TGF-β1 Derived from Dermal Papilla Cells as a Key Mediator in Androgenetic Alopecia Journal of Investigative Dermatology Symposium Proceedings · 2003

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    1. Garlic Exosomes Promote Hair Growth Through the Wnt/Beta-Catenin Pathway and Growth Factors Cureus · 2023