Alopecia Associated With Zidovudine Therapy

    Sandra M. Geletko, Marisel Segarra, Dennis J. Mikolich
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    TLDR Zidovudine may cause hair loss in advanced-stage HIV patients.
    The document described a case where a 33-year-old HIV-infected man developed alopecia areata after beginning treatment with zidovudine, a medication for HIV. The alopecia persisted despite a reduced dosage of zidovudine, but hair regrowth occurred after the drug was stopped, even though the patient's CD4+ count was zero. This case was notable because alopecia had not been previously reported as a side effect of zidovudine, and the patient's refusal to restart the medication prevented further investigation to definitively establish zidovudine as the cause. The authors noted that while zidovudine might promote hair growth in HIV patients with higher CD4+ counts, it could cause hair loss in those with advanced-stage infection, although the exact mechanism was unclear.
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      in Treatment  2 upvotes 3 years ago
      A user with alopecia totalis, borderline universalis, seeks advice on getting into a Xeljanz trial or appealing insurance for coverage. They experienced significant hair regrowth but are now seeing hair loss again and want to try Xeljanz.

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      A 19-year-old male has been using topical finasteride and minoxidil for 8 months with no progress and is considering seeking a second opinion due to potential misdiagnosis. The discussion revolves around whether the hair loss is due to male pattern baldness, alopecia areata, or a vitamin deficiency.

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