A Rare Type of Radiation-Induced Alopecia: Proton-Induced Alopecia

    January 2023 in “ Skin appendage disorders ”
    Davide Fattore, Vincenzo Picone, Maria Vastarella, Gabriella Fabbrocini, Maria Teresa Cantelli
    Image of study
    TLDR A woman's hair grew back after treatment for a rare hair loss caused by proton therapy.
    Proton-induced alopecia (PIA) is a rare form of radiation-induced alopecia (RIA) that occurs following proton therapy (PT) for brain tumors. This case report details a 38-year-old female who developed diffuse hair loss in the frontal region after PT for a meningioma. Trichoscopy showed typical signs of PIA, and treatment with topical minoxidil 5% resulted in complete hair regrowth within 4 months. PIA is caused by radiation damage to hair follicles in the anagen phase, leading to disrupted mitotic activity and increased hair fragility. The study emphasizes the need for more research on PIA as the use of PT grows.
    Discuss this study in the Community →

    Research cited in this study

    4 / 4 results

    Related Community Posts Join

    6 / 9 results

      community Sometimes the hair loss was in our control the whole time

      in Chat  809 upvotes 2 weeks ago
      The conversation discusses hair loss and the potential impact of diet and lifestyle changes, particularly increased protein intake, on hair health. The original poster shared their experience of improved hair appearance after weight loss and dietary changes, despite skepticism from others about lighting differences in photos and the effectiveness of diet alone without finasteride or minoxidil.

      community Binding affinity of pyrilutamide!

      in Update  170 upvotes 3 years ago
      Pyrilutamide, a nonsteroidal antiandrogen drug under development for the potential treatment of androgenic alopecia. The conversation discusses its binding affinity to the androgen receptor and the timeline for possible availability after trials are completed in the United States and China.

      community 6 month progress. Fin/Min daily.

      in Progress Pictures  506 upvotes 4 years ago
      A user's 6 month progress using finasteride and minoxidil as treatments for hair loss, with the replies discussing side effects and general consensus about usage of the two medications.

      community [Theory] Big Bald is deliberately delaying the cure indefinitely

      in Satire  346 upvotes 4 weeks ago
      The conversation humorously suggests that the hair loss industry, referred to as "Big Bald," deliberately delays a cure to profit from ongoing treatments like minoxidil, finasteride, and dutasteride. Participants debate whether a cure would be more profitable than current treatments, with some suggesting that the industry prefers continuous treatments for sustained profit.

      community 3 months progress- back from the dead?

      in Progress Pictures  576 upvotes 1 month ago
      A 32-year-old is documenting their 3-month progress in treating hair loss using 0.5 mg dutasteride, topical and 5 mg oral minoxidil, and Ducray Anaphase+ shampoo daily. They report slight libido reduction and increased eyebrow hair but are generally satisfied with the results and considering a hair transplant after a year.

    Related Research

    9 / 9 results