Androgenetic Alopecia

January 2018

Pooya Khan Mohammad Beigi

androgenetic alopecia AGA terminal hairs vellus hairs androgen-dependent hereditary condition balding patterns therapies hair loss balding

TLDR Androgenetic alopecia (AGA) is a common, hereditary hair loss condition that can be slowed but not permanently reversed with available therapies.

Androgenetic alopecia (AGA) is the most prevalent form of hair loss, characterized by the transformation of terminal hairs into thin vellus hairs due to androgen-dependent events. It is a hereditary condition with distinct patterns of balding in males and females. As of 2017, there was no permanent reversal for AGA, but several therapies were available to slow and potentially reverse the progression of hair loss.

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6 / 6 results

research Conditions Simulating Androgenetic Alopecia

6 citations , July 2015 in “Journal of The European Academy of Dermatology and Venereology”

Different hair loss types need accurate diagnosis for proper treatment.

research Evidence-Based Guideline for the Treatment of Androgenetic Alopecia in Women and Men

198 citations , October 2011 in “Journal der Deutschen Dermatologischen Gesellschaft”

Use minoxidil for hair loss; finasteride and dutasteride for men, dutasteride for women.

research Male Androgenetic Alopecia

100 citations , May 2010 in “Expert Opinion on Pharmacotherapy”

Hair loss in men treated best with early medication or transplant, new treatments researched.

research Androgenetic Alopecia: Clinical Features, Classification, and Treatments

103 citations , June 2007 in “Endocrinology and Metabolism Clinics of North America”

Male pattern hair loss is genetic and influenced by hormones, with treatments like minoxidil and surgery available.

research Prevalence of Male and Female Pattern Hair Loss in Maryborough

193 citations , December 2005 in “Journal of Investigative Dermatology Symposium Proceedings”

Hair loss common in Australia; men affected earlier, more often than Asians; women less concerned.

research Female Pattern Hair Loss

226 citations , September 2001 in “Journal of The American Academy of Dermatology”

Hair loss in women is genetic, diagnosed by examination and biopsy, and treated with minoxidil, finasteride, or transplantation.

3 / 3 results

research Skin and Hair Abnormalities of Cantu Syndrome: A Congenital Hypertrichosis Due to a Genetic Alteration Mimicking the Pharmacological Effect of Minoxidil

7 citations , January 2020 in “Journal of Dermatology”

Cantu syndrome, which causes excessive hair growth and skin issues, is due to a mutation in the ABCC9 gene, and understanding this could help develop new treatments for hair diseases.

research Primary Follicular Dystrophy With Scarring Dermatitis in C57BL/6 Mouse Substrains Resembles Central Centrifugal Cicatricial Alopecia in Humans

56 citations , September 2010 in “Veterinary pathology”

Certain mouse strains develop a skin condition similar to a human hair loss disease due to genetic defects.

research Atrichia Caused by Mutations in the Vitamin D Receptor Gene Is a Phenocopy of Generalized Atrichia Caused by Mutations in the Hairless Gene

139 citations , September 2001 in “The journal of investigative dermatology/Journal of investigative dermatology”

Mutations in the Vitamin D receptor gene can cause hair loss similar to mutations in the Hairless gene.