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Glossary Radiation-Induced Alopecia

hair loss caused by radiation therapy damaging hair follicles

Radiation-Induced Alopecia, also known as Radiation Hair Loss, refers to hair loss that occurs as a result of exposure to radiation therapy, commonly used in cancer treatment. The radiation damages the hair follicles in the targeted area, leading to temporary or sometimes permanent hair loss depending on the dose and duration of the treatment.

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Research

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research Assessment and Treatment Outcomes of Persistent Radiation-Induced Alopecia in Patients With Cancer

24 citations , August 2020 in “JAMA dermatology”

In this study, researchers observed a dose-dependent occurrence of persistent radiation-induced alopecia in patients with primary CNS tumors or head and neck sarcomas, noting distinctive patterns and features, and suggesting potential benefits of topical minoxidil and procedural interventions for treatment.

research Radiation-induced alopecia

17 citations , January 2010 in “International journal of trichology”

This case report highlights the occurrence of radiation-induced alopecia in a patient undergoing radiotherapy for oropharyngeal carcinoma, emphasizing awareness of this potential side effect.

research Dermoscopic Findings in Radiation-Induced Alopecia after Angioembolization

13 citations , January 2014 in “Dermatology”

This study reported that alopecic lesions after radiation exposure during angioembolization share dermoscopic features with alopecia areata, highlighting the importance of accurate patient history to avoid misdiagnosis.

research Radiation-induced Alopecia Treated with Botulinum Toxin Type A Injection

10 citations , October 2014 in “Plastic & Reconstructive Surgery Global Open”

In this case study, Botulinum toxin type A injections were associated with improved hair growth and scalp condition in a patient with radiation-induced alopecia, though the mechanisms remain speculative.

research Temporary radiation-induced alopecia after embolization of a cerebral arteriovenous malformation

9 citations , October 2014 in “Clinical and Experimental Dermatology”

Temporary hair loss can occur after brain AVM treatment but usually regrows in 8 weeks.

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Community Join

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Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

community Compressed part of research of theory of androgenic/anabolitic balance. AGA h-responders analytic. Theory of physio-metabolitic method of anti AGA treatment

in Research 865 upvotes 1 year ago

The treatment for androgenetic alopecia involves using finasteride and minoxidil with intense exercise and cold exposure to boost metabolism and reduce androgenic effects, potentially leading to hair regrowth. This approach may activate biological pathways for improved hair and overall health.

community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

in Research 830 upvotes 2 years ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

community Other factors involved then DHT/5aR

5 upvotes 3 months ago

DHT is the primary cause of hair loss, but factors like diet, stress, and lifestyle can influence its severity. Treatments like finasteride and dutasteride target DHT, while maintaining overall health is also important.

community My finasteride progress in a 6 month

1282 upvotes 8 months ago

Successful hair regrowth after six months using finasteride and topical minoxidil, with minimal side effects like anxiety. Finasteride was the main treatment, and minoxidil supported regrowth.

community Everyone is ignoring that plasma finasteride levels are 100x lower with topical compared to oral.

in Research/Science 140 upvotes 2 years ago

Topical finasteride results in plasma levels 100 times lower than oral finasteride, potentially reducing systemic side effects. Users report similar efficacy with fewer side effects, suggesting a preference for topical application.

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Learn

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learn Alopecia Areata

autoimmune disorder causing patchy hair loss

learn Alfatradiol

Alfatradiol: Can it help if my hair loss is linked to DHT? The one randomised trial of topical alfatradiol — in 103 women — found hair thickness and density essentially unchanged after six months, while minoxidil improved both; its authors credited alfatradiol with slowing hair loss rather than regrowing hair. Laboratory work supports a local effect on follicular DHT, but no controlled trial in men appears to have been published.
Alfatradiol: What does a form of estrogen have to do with hair loss in men? Alfatradiol (17α-estradiol) is a prescription topical hormone, licensed for androgenetic alopecia in Germany but not FDA-approved. The controlled trial evidence is in women, where it produced stabilisation rather than regrowth and was outperformed by minoxidil; no comparable placebo-controlled trial in men appears to have been published.

learn RU58841

Will I lose my hair if I stop using RU58841? (Spoiler: I might.) There is no published human trial of stopping RU58841; community members commonly report shedding within weeks to months, and androgen biology suggests miniaturization would resume once the topical anti-androgen is withdrawn.

learn TDM-105795

What types of alopecia or hair loss conditions might TDM-105795 be designed to target based on current research? TDM-105795 may target non-scarring alopecia, particularly androgenetic alopecia.

learn Tofacitinib

a JAK inhibitor for alopecia areata and other autoimmune conditions

learn Vitamin D

Are topical Vitamin D treatments useful for alopecia? Topical Vitamin D treatments may help some individuals with alopecia.

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