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      learn HMI-115

      much-hyped research compound targeting prolactin receptor in scalp

      learn Pyrilutamide

      highly targeted anti-androgen that might have minimal systemic effects

      learn Valproic acid

      an anticonvulsant repurposed for hair loss via histone inhibition

      learn PP405

      mitochondrial pyruvate carrier (MPC) inhibitor by Pelage in early trials

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      community Binding affinity of pyrilutamide!

      in Update  168 upvotes 3 years ago
      Pyrilutamide, a nonsteroidal antiandrogen drug under development for the potential treatment of androgenic alopecia. The conversation discusses its binding affinity to the androgen receptor and the timeline for possible availability after trials are completed in the United States and China.

      community Creatine made all my high DHT symptoms return

      in Research/Science  82 upvotes 1 year ago
      Creatine may increase DHT levels, potentially causing symptoms like acne, oily hair, and hair shedding. Users report mixed experiences, with some avoiding creatine due to hair loss concerns and others seeing no impact.

      community Waiting to start treatment until Kintor KX-826 Phase 2 data is published?

      in Chat  17 upvotes 3 years ago
      People are waiting for KX-826 (Pyrilutamide) Phase 2 data to decide on hair loss treatments, with some considering finasteride or minoxidil in the meantime. Pyrilutamide is seen as a potentially stronger and safer alternative to finasteride, but concerns about side effects and availability remain.