Comparative Clinical Study Evaluating the Efficacy and Safety of Topical 5% Cetosomal Minoxidil and Topical 5% Alcohol-Based Minoxidil Solutions for the Treatment of Androgenetic Alopecia in Indian Men

    October 2023 in “ Cureus ”
    Sandeep Sattur, Abhay Talathi, Geetanjali Shetty … Dhiraj Dhoot
    Studysummary This study compared the safety and effectiveness of 5% cetosomal minoxidil to 5% alcohol-based minoxidil in Indian men with androgenetic alopecia, finding that cetosomal minoxidil had improved safety and similar efficacy, making it a potentially better option for those sensitive to alcohol-based formulations.
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    Research cited in this study 21

    1. Real-World Effectiveness, Safety, and Tolerability of Cetosomal Minoxidil 5% Alone and in Combination With Finasteride 0.1% in the Management of Androgenetic Alopecia Cureus · 2023
    2. Treatment Options for Androgenetic Alopecia: Efficacy, Side Effects, Compliance, Financial Considerations, and Ethics Journal of Cosmetic Dermatology · 2021
    3. A Randomized, Double-Blind Controlled Clinical Study to Evaluate the Efficacy and Safety of Minoxidil Topical 2% Nanosuspension with Aqueous Base in the Treatment of Androgenetic Alopecia Areata Journal of reports in pharmaceutical sciences · 2021
    4. SULT1A1 (Minoxidil Sulfotransferase) Enzyme Booster Significantly Improves Response to Topical Minoxidil for Hair Regrowth Journal of Cosmetic Dermatology · 2021
    5. Novel 'After Minoxidil' Spray Improves Topical Minoxidil Compliance and Hair Style Manageability Journal of Cosmetic Dermatology · 2020
    6. Comparative Study to Evaluate Tolerability of Topical 5% Minoxidil Novel Formulation and Alcohol-Based Conventional Solutions in Treatment of Androgenetic Alopecia in Indian Men: Randomized Double-Blind Study Dermatology and therapy · 2020
    7. Topical Minoxidil-Loaded Nanotechnology Strategies for Alopecia Cosmetics · 2020
    8. Minoxidil And Its Use In Hair Disorders: A Review Drug Design Development and Therapy · 2019
    9. A Randomized, Double-Blind Controlled Study of the Efficacy and Safety of Topical Solution of 0.25% Finasteride Admixed with 3% Minoxidil vs. 3% Minoxidil Solution in the Treatment of Male Androgenetic Alopecia Journal of The European Academy of Dermatology and Venereology · 2018
    10. Dermoscopy Is the Crucial Step for Proper Outcome Prospection When Treating Androgenetic Alopecia with the Regenera Protocol: A Score Proposal International Journal of Clinical and Developmental Anatomy · 2018
    11. The Effectiveness of Treatments for Androgenetic Alopecia: A Systematic Review and Meta-Analysis Journal of The American Academy of Dermatology · 2017
    12. Efficacy and Safety of 5% Minoxidil Topical Foam in Male Pattern Hair Loss Treatment and Patient Satisfaction Acta dermatovenerologica Alpina, Pannonica et Adriatica (Tiskana izd.) · 2016
    13. Effect of Minoxidil Topical Foam on Frontotemporal and Vertex Androgenetic Alopecia in Men: A 104-Week Open-Label Clinical Trial Journal of The European Academy of Dermatology and Venereology · 2015
    14. Quality of Life Assessment in Male Patients with Androgenetic Alopecia: Results of a Prospective, Multicenter Study Annals of Dermatology · 2012
    15. Clinical Severity Does Not Reliably Predict Quality of Life in Women With Alopecia Areata, Telogen Effluvium, or Androgenic Alopecia Journal of The American Academy of Dermatology · 2011
    16. Transcutol-Containing Vesicles for Topical Delivery of Minoxidil Journal of Drug Targeting · 2010
    17. A Multicenter, Randomized, Placebo-Controlled, Double-Blind Clinical Trial of a Novel Formulation of 5% Minoxidil Topical Foam Versus Placebo in the Treatment of Androgenetic Alopecia in Men Journal of The American Academy of Dermatology · 2007
    18. A Randomized, Placebo-Controlled Trial of 5% and 2% Topical Minoxidil Solutions in the Treatment of Female Pattern Hair Loss Journal of The American Academy of Dermatology · 2004
    19. A Randomized Clinical Trial of 5% Topical Minoxidil Versus 2% Topical Minoxidil and Placebo in the Treatment of Androgenetic Alopecia in Men Journal of The American Academy of Dermatology · 2002
    20. The Psychosocial Consequences of Androgenetic Alopecia: A Review of the Research Literature British Journal of Dermatology · 1999
    21. Long-Term Efficacy of Topical Minoxidil in Male Pattern Baldness Journal of The American Academy of Dermatology · 1987

    Related research 8

    1. Minoxidil Sulfotransferase Enzymatical Activity in Plants: A Novel Paradigm in Increasing Minoxidil Response in Androgenetic Alopecia Journal of Cosmetic Dermatology · 2023
    2. Compliance to Topical Minoxidil and Reasons for Discontinuation Among Patients With Androgenetic Alopecia Dermatology and therapy · 2023
    3. Tretinoin Enhances Minoxidil Response in Androgenetic Alopecia Patients by Upregulating Follicular Sulfotransferase Enzymes Dermatologic Therapy · 2019
    4. The Use of Minoxidil in the Treatment of Male and Female Androgenetic Alopecia: A Story of More Than 30 Years Italian journal of dermatology and venereology · 2018
    5. A Randomized Clinical Trial of 5% Topical Minoxidil Versus 2% Topical Minoxidil and Placebo in the Treatment of Androgenetic Alopecia in Men Journal of The American Academy of Dermatology · 2002
    6. Androgenetic Alopecia: Treatment Results with Topical Minoxidil Journal of The American Academy of Dermatology · 1987
    7. Topical Minoxidil (3%) in Extensive Alopecia Areata, Including Long-Term Efficacy Journal of The American Academy of Dermatology · 1987
    8. Topical Minoxidil Therapy and Hair Regrowth Archives of Dermatology · 1985