SULT1A1 (Minoxidil Sulfotransferase) Enzyme Booster Significantly Improves Response to Topical Minoxidil for Hair Regrowth

    June 2021 in “ Journal of Cosmetic Dermatology ”
    Rachita Dhurat, Sanober Burzin Daruwalla, Suraj Pai … Andy Goren
    Studysummary In this study, the addition of a SULT1A1 enzyme booster to daily 5% minoxidil treatment significantly increased hair regrowth in men with androgenic alopecia compared to minoxidil alone.
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    Research cited in this study 8

    1. Novel 'After Minoxidil' Spray Improves Topical Minoxidil Compliance and Hair Style Manageability Journal of Cosmetic Dermatology · 2020
    2. Minoxidil Sulfotransferase Enzyme (SULT1A1) Genetic Variants Predict Response to Oral Minoxidil Treatment for Female Pattern Hair Loss Journal of The European Academy of Dermatology and Venereology · 2020
    3. Novel Topical Booster Enhances Follicular Sulfotransferase Activity in Patients with Androgenetic Alopecia: A New Strategy to Improve Minoxidil Response Journal of The European Academy of Dermatology and Venereology · 2020
    4. Characterization of Follicular Minoxidil Sulfotransferase Activity in a Cohort of Pattern Hair Loss Patients from the Indian Subcontinent Dermatologic Therapy · 2018
    5. Clinical Utility and Validity of Minoxidil Response Testing in Androgenetic Alopecia Dermatologic Therapy · 2014
    6. A Multicenter, Randomized, Placebo-Controlled, Double-Blind Clinical Trial of a Novel Formulation of 5% Minoxidil Topical Foam Versus Placebo in the Treatment of Androgenetic Alopecia in Men Journal of The American Academy of Dermatology · 2007
    7. Minoxidil Sulfotransferase, A Marker Of Human Keratinocyte Differentiation Journal of Investigative Dermatology · 1992
    8. Minoxidil Sulfate Is the Active Metabolite That Stimulates Hair Follicles Journal of Investigative Dermatology · 1990

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    2. Sisaipho Alopecia Areata Treated With Tofacitinib and Oral Minoxidil JAAD case reports · 2022
    3. Efficacy of Systemic Minoxidil and Tofacitinib Combination in Treatment-Resistant Alopecia Universalis Journal of Cosmetic Dermatology · 2020
    4. Oral Minoxidil Improves Background Hair Thickness in Lichen Planopilaris Journal of The American Academy of Dermatology · 2020
    5. Pustular Dermatosis of the Scalp Due to Topical Minoxidil 5% 2018
    6. Scalp Psoriasiform Contact Dermatitis with Acute Telogen Effluvium Due to Topical Minoxidil Treatment Skin appendage disorders · 2015
    7. Hair Growth Therapies for Androgenetic Alopecia Archives of Dermatology · 1996
    8. Use of Topical Minoxidil Therapy for Androgenetic Alopecia in Women International Journal of Dermatology · 1993
    9. Treatment of Female Androgenetic Alopecia with Minoxidil 2% International Journal of Dermatology · 1992