learn Tretinoin
the gold standard retinoid in dermatology that's also helpful for hair regrowth alongside Minoxidil
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learn Osteopontin
signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss
learn Minoxidil
An essential vasodilator with some anti-androgenic effects, has excellent safety record
learn Alfatradiol
a synthetic estrogen used topically as an anti-androgen
Research
5 / 1000+ results
research Sulfation of Minoxidil by Multiple Human Cytosolic Sulfotransferases
Minoxidil breakdown varies by enzymes, affecting hair loss treatment effectiveness.
research Localization of Minoxidil Sulfotransferase in Rat Liver and the Outer Root Sheath of Anagen Pelage and Vibrissa Follicles
Minoxidil works in liver and outer hair root sheath for hair growth.
research Food Deprivation-Induced Expression of Minoxidil Sulfotransferase in the Hypothalamus Uncovered by Microarray Analysis
Food deprivation increases MST enzyme in the brain, possibly affecting energy balance.
research Minoxidil Sulfotransferase, A Marker Of Human Keratinocyte Differentiation
Minoxidil sulfotransferase is a marker of keratinocyte differentiation and may play a role in hair growth.
research Tretinoin Enhances Minoxidil Response in Androgenetic Alopecia Patients by Upregulating Follicular Sulfotransferase Enzymes
Tretinoin boosts minoxidil's effect on hair loss by increasing enzyme activity.
Community Join
5 / 1000+ resultscommunity Minoxidil: Sulfotransferase Enzyme booster AVAILABLE NOW
A new product, Minoxidil booster, which enhances sulfotransferase enzyme activity in the scalp, is now available. The user has started using this product, applied before Minoxidil, to improve their hair loss treatment results.
community Minoxidil Response Bottlenecks: Why Sulfation and Transport Matter (And Where Tretinoin Fits In)
Minoxidil's effectiveness is limited by the need for sulfation and proper transport to hair follicles, with tretinoin potentially enhancing its effects by promoting enzyme activity and keratinocyte differentiation. Tretinoin may improve minoxidil's response by boosting the expression of necessary enzymes and transporters.
community Started applying minoxidil to my whole scalp a couple months ago rather than just to my crown— is this sort of shedding normal?
Shedding is common with minoxidil, and it often indicates new hair growth. Users discuss experiences with minoxidil, finasteride, and dutasteride, noting that results can vary and patience is needed.
community Painkillers May Block Minoxidil
Painkillers like Aspirin may reduce Minoxidil's effectiveness by inhibiting the enzyme PGHS-1, which is crucial for hair growth. Using NSAIDs that inhibit COX-2 or combining Minoxidil with PGF2/E2 analogues or retinoids may enhance its efficacy.
community DLQ01: A Better "Minoxidil" PGF2a synthetic analogue.
DLQ01, a prostaglandin F2α analog, shows promise for hair growth by directly stimulating PGE2/PGF receptors without needing conversion, and can be combined with minoxidil and retinoids like tretinoin for enhanced effectiveness. Minoxidil's efficacy may be reduced by COX-1 inhibitors, but using prostaglandin analogs like Latanoprost or Bimatoprost can help maintain its effectiveness.