The Hair Loss Encyclopedia

Novel Topical Booster Enhances Follicular Sulfotransferase Activity in Patients with Androgenetic Alopecia: A New Strategy to Improve Minoxidil Response

December 2020 in “ Journal of The European Academy of Dermatology and Venereology ”

Pablo Ramos, J. Philip McCoy, Carlos Gustavo Wambier, Joseph I. Shapiro, Sergio Vano-Galvan, Robert Sinclair, Amir Goren

topical booster follicular sulfotransferase activity androgenetic alopecia minoxidil hair loss AGA Rogaine

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TLDR Topical booster improves hair loss treatment effectiveness.

A study investigated the use of a novel topical booster to enhance follicular sulfotransferase activity in patients with androgenetic alopecia (AGA) and improve their response to minoxidil treatment. The booster was found to significantly increase sulfotransferase activity and improve minoxidil response in patients with AGA. This suggests that the use of topical boosters may be a new strategy to improve the efficacy of minoxidil treatment for hair loss. The study involved 20 patients with AGA and lasted for 14 days.

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8 / 8 results

research Minoxidil 1 mg Oral Versus Minoxidil 5% Topical Solution for the Treatment of Female-Pattern Hair Loss: A Randomized Clinical Trial

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research Oral Minoxidil Bio-Activation by Hair Follicle Outer Root Sheath Cell Sulfotransferase Enzymes Predicts Clinical Efficacy in Female Pattern Hair Loss

9 citations , January 2020 in “Journal of The European Academy of Dermatology and Venereology”

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research The Effectiveness of Treatments for Androgenetic Alopecia: A Systematic Review and Meta-Analysis

178 citations , July 2017 in “Journal of The American Academy of Dermatology”

Minoxidil, finasteride, and low-level laser light therapy effectively treat hair loss.

research Clinical Utility and Validity of Minoxidil Response Testing in Androgenetic Alopecia

43 citations , January 2015 in “Dermatologic Therapy”

Minoxidil response testing helps treat hair loss effectively and safely.

research Novel Enzymatic Assay Predicts Minoxidil Response in the Treatment of Androgenetic Alopecia

27 citations , May 2014 in “Dermatologic Therapy”

New test predicts if hair loss treatment will work.

research Minoxidil Sulfotransferase, a Marker of Human Keratinocyte Differentiation

16 citations , May 1992 in “Journal of Investigative Dermatology”

Minoxidil sulfotransferase is a marker of keratinocyte differentiation and may play a role in hair growth.

research Minoxidil Sulfate Is the Active Metabolite that Stimulates Hair Follicles

166 citations , November 1990 in “Journal of Investigative Dermatology”

Minoxidil sulfate stimulates hair growth.

research Sulfation of minoxidil by human liver phenol sulfotransferase

68 citations , September 1990 in “Biochemical Pharmacology”

Minoxidil activates hair growth by being sulfated by P-PST in the human liver.

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3 / 3 results

research Pustular Dermatosis of the Scalp Due to Topical Minoxidil 5%

3 citations , January 2018

A woman had an unusual allergic reaction to a hair loss treatment, which cleared up after stopping the treatment and using a different medication.

research Effectivity of Minoxidil as a Treatment for Alopecia Areata

January 2014 in “DOAJ (DOAJ: Directory of Open Access Journals)”

research Alopecia areata treated with topical minoxidil

16 citations , April 1984 in “Archives of Dermatology”

Topical minoxidil can help hair regrowth in alopecia areata patients, but maintaining the growth after stopping treatment is inconsistent.