Novel Topical Booster Enhances Follicular Sulfotransferase Activity in Patients with Androgenetic Alopecia: A New Strategy to Improve Minoxidil Response

May 2020 in “ Journal of The European Academy of Dermatology and Venereology ”

Pablo Ramos, J. Philip McCoy, Carlos Gustavo Wambier, Joseph I. Shapiro, Sergio Vano-Galvan, Robert Sinclair, Amir Goren

topical booster follicular sulfotransferase activity androgenetic alopecia minoxidil hair loss AGA Rogaine

TLDR Topical booster improves hair loss treatment effectiveness.

A study investigated the use of a novel topical booster to enhance follicular sulfotransferase activity in patients with androgenetic alopecia (AGA) and improve their response to minoxidil treatment. The booster was found to significantly increase sulfotransferase activity and improve minoxidil response in patients with AGA. This suggests that the use of topical boosters may be a new strategy to improve the efficacy of minoxidil treatment for hair loss. The study involved 20 patients with AGA and lasted for 14 days.

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Research cited in this study

8 / 8 results

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research Sulfation of Minoxidil by Human Liver Phenol Sulfotransferase

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Novel Topical Booster Enhances Follicular Sulfotransferase Activity in Patients with Androgenetic Alopecia: A New Strategy to Improve Minoxidil Response

Research cited in this study

research Minoxidil 1 mg Oral Versus Minoxidil 5% Topical Solution for the Treatment of Female-Pattern Hair Loss: A Randomized Clinical Trial

research Oral Minoxidil Bio-Activation by Hair Follicle Outer Root Sheath Cell Sulfotransferase Enzymes Predicts Clinical Efficacy in Female Pattern Hair Loss

research The Effectiveness of Treatments for Androgenetic Alopecia: A Systematic Review and Meta-Analysis

research Clinical Utility and Validity of Minoxidil Response Testing in Androgenetic Alopecia

research Novel Enzymatic Assay Predicts Minoxidil Response in the Treatment of Androgenetic Alopecia

research Minoxidil Sulfotransferase, A Marker Of Human Keratinocyte Differentiation

research Minoxidil Sulfate Is the Active Metabolite That Stimulates Hair Follicles

research Sulfation of Minoxidil by Human Liver Phenol Sulfotransferase

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