Novel Topical Booster Enhances Follicular Sulfotransferase Activity in Patients with Androgenetic Alopecia: A New Strategy to Improve Minoxidil Response

    May 2020 in “ Journal of The European Academy of Dermatology and Venereology ”
    Pablo Ramos, J. Philip McCoy, Carlos Gustavo Wambier … Amir Goren
    Studysummary This paper introduces a novel topical booster aimed at enhancing follicular sulfotransferase activity to potentially improve minoxidil response in patients with androgenetic alopecia but reports no new clinical results.
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    Research cited in this study 8

    1. Minoxidil 1 mg Oral Versus Minoxidil 5% Topical Solution for the Treatment of Female-Pattern Hair Loss: A Randomized Clinical Trial Journal of The American Academy of Dermatology · 2019
    2. Oral Minoxidil Bio-Activation by Hair Follicle Outer Root Sheath Cell Sulfotransferase Enzymes Predicts Clinical Efficacy in Female Pattern Hair Loss Journal of The European Academy of Dermatology and Venereology · 2019
    3. The Effectiveness of Treatments for Androgenetic Alopecia: A Systematic Review and Meta-Analysis Journal of The American Academy of Dermatology · 2017
    4. Clinical Utility and Validity of Minoxidil Response Testing in Androgenetic Alopecia Dermatologic Therapy · 2014
    5. Novel Enzymatic Assay Predicts Minoxidil Response in the Treatment of Androgenetic Alopecia Dermatologic Therapy · 2013
    6. Minoxidil Sulfotransferase, A Marker Of Human Keratinocyte Differentiation Journal of Investigative Dermatology · 1992
    7. Minoxidil Sulfate Is the Active Metabolite That Stimulates Hair Follicles Journal of Investigative Dermatology · 1990
    8. Sulfation of Minoxidil by Human Liver Phenol Sulfotransferase Biochemical Pharmacology · 1990

    Related research 5

    1. Allergic Contact Dermatitis Due to Minoxidil in a Patient With Alopecia Areata Actas Dermo-Sifiliográficas · 2022
    2. Pustular Dermatosis of the Scalp Due to Topical Minoxidil 5% 2018
    3. Effectivity of Minoxidil as a Treatment for Alopecia Areata DOAJ (DOAJ: Directory of Open Access Journals) · 2013
    4. Topical Minoxidil in the Treatment of Alopecia Areata Plastic & Reconstructive Surgery · 1985
    5. Alopecia Areata Treated With Topical Minoxidil Archives of Dermatology · 1984