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a topical anti-androgen with less systemic involvement
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powerful topical and oral anti-androgen used mostly by women
learn Clascoterone
a novel topical treatment that inhibits DHT on androgen receptors
learn RU58841
a potent but unapproved and potentially problematic topical anti-androgen
learn Melatonin
hormone commonly taken for sleep aid has some topical benefits for hair
Research
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research Novel Topical Booster Enhances Follicular Sulfotransferase Activity in Patients with Androgenetic Alopecia: A New Strategy to Improve Minoxidil Response
Topical booster improves hair loss treatment effectiveness.
research SULT1A1 (Minoxidil Sulfotransferase) Enzyme Booster Significantly Improves Response to Topical Minoxidil for Hair Regrowth
Enzyme booster SULT1A1 greatly enhances hair regrowth with minoxidil.
research SULT1A1 Enzyme Booster to Amplify Topical Minoxidil Response in Androgenic Alopecia: A Single-Center Prospective Study
The SULT1A1 enzyme booster improves minoxidil effectiveness in treating hair loss, especially in females.
research Minoxidil Sulfotransferase Enzymatical Activity in Plants: A Novel Paradigm in Increasing Minoxidil Response in Androgenetic Alopecia
Some plants like spinach, broccoli, and matcha may boost the effectiveness of the hair growth drug minoxidil.
research Androgenetic Alopecia – Update 2022
Community Join
5 / 1000+ resultscommunity Increasing activity of the sult1a1 enzyme via alkalizing agent and tretinoin for better response to topical minoxidil
Increasing the sult1a1 enzyme on the scalp may improve response to topical minoxidil. The user suggests using a baking soda solution, DMSO, and tretinoin to enhance enzyme activity and minoxidil effectiveness.
community Topical minoxidil + Age-R Booster-H-device = Vast improvements in my hair recovery.
The user reported significant hair recovery using topical minoxidil combined with the Age-R Booster-H-device, alongside oral finasteride and weekly dermaroller use. The device improved minoxidil absorption, leading to visible new hair growth.
community MinoxiBoost - SULT1A1 Enzyme booster journey
The user has tried topical Minoxidil and oral Minoxidil for beard and scalp hair growth with minimal results, and has been on Finasteride for 7 months with stabilized scalp hair but no facial hair improvement. They are considering using a SULT1A1 enzyme booster to enhance results and are questioning its effectiveness without concurrent topical Minoxidil application.
community This true? Sult1a1 enzyme booster 2025
The conversation discusses the potential effectiveness of a Sult1a1 enzyme booster in enhancing the results of minoxidil for hair loss. Users express interest in the booster, hoping it will improve the effectiveness of oral minoxidil, especially for those who struggle with topical application.
community Oral minoxidil vs Topical Minoxidil w/ Retinoic acid
Topical minoxidil with retinoic acid is effective but causes scalp irritation, leading the user to consider switching to 2.5mg oral minoxidil. Oral minoxidil may cause body hair growth and heart-related side effects, so it's advised to use it under medical guidance.