Real-World Effectiveness, Safety, and Tolerability of Cetosomal Minoxidil 5% Alone and in Combination With Finasteride 0.1% in the Management of Androgenetic Alopecia

July 2023 in “ Cureus ”

Amit Shivaji Kerure, Mansukh Ghalla, Satyaprakash Mahajan, Dhiraj Dhoot, Hanmant Barkate

cetosomal minoxidil minoxidil finasteride androgenetic alopecia AGA scaling Rogaine Propecia

TLDR Cetosomal minoxidil alone and with finasteride is effective and well-tolerated for hair loss treatment.

The study analyzed the effectiveness and safety of cetosomal minoxidil 5% alone and in combination with finasteride 0.1% in treating androgenetic alopecia (AGA) in 261 patients across 66 centers in India. The results showed that 52% of patients using cetosomal minoxidil alone (Group I) and 68% of those using the combination (Group II) saw significant to excellent improvement after 16 weeks. The product's tolerability was rated as excellent by 64% of Group I and 69% of Group II. In terms of cosmetic acceptability, 64% of Group I and 74% of Group II rated the product as excellent. Only one patient in Group I reported an adverse event (scaling), which resolved spontaneously. The study concluded that cetosomal-based minoxidil solutions are effective and tolerable in managing AGA and could serve as alternatives to alcoholic formulations.

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