TLDR Minoxidil and pyrithione zinc combo most effectively increases hair density.
A 6-month randomized controlled trial was conducted on 200 healthy men with Hamilton-Norwood type III vertex or type IV baldness to assess the hair growth benefits of a 1% pyrithione zinc shampoo compared to a 5% minoxidil topical solution, a placebo shampoo, and a combination of the two. Hair count results showed a significant increase in total visible hair counts for the 1% pyrithione zinc shampoo, the 5% minoxidil topical solution, and the combination treatment groups relative to the placebo shampoo after 9 weeks of treatment. The study concluded that daily use of a 1% pyrithione zinc shampoo over a 26-week treatment period can result in a modest and sustained improvement in hair growth. The combination of minoxidil and pyrithione zinc was found to be more effective in increasing hair density than either treatment alone.
92 citations,
January 1998 in “Dermatology” Ketoconazole shampoo improves hair growth and reduces oil similarly to minoxidil in male pattern hair loss.
102 citations,
October 1996 in “Dermatologic Clinics” Photographic documentation crucial for evaluating hair growth in androgenetic alopecia.
40 citations,
January 1996 in “Journal of Dermatological Treatment” Antimicrobial lotion reduces inflammation and increases hair density in hair loss patients.
1 citations,
October 2022 in “PubMed” Patients generally have positive attitudes towards using topical Minoxidil for hair loss treatment.
1 citations,
August 2022 in “JAAD case reports” Tofacitinib and oral minoxidil may help treat Sisaipho alopecia areata.
July 2022 in “Journal of Investigative Dermatology” Scalp clarifying shampoo can help reduce hair loss and improve hair volume.
3 citations,
January 2018 A woman had an unusual allergic reaction to a hair loss treatment, which cleared up after stopping the treatment and using a different medication.
4 citations,
July 2015 in “Clinical, cosmetic and investigational dermatology” The shampoo is very effective and safe for use after hair transplants.
14 citations,
January 2015 in “Skin appendage disorders” Minoxidil treatment for hair loss can cause scalp allergy and severe hair loss.
58 citations,
October 1993 in “International Journal of Dermatology” Minoxidil helps hair growth and reduces shedding in women.
43 citations,
November 1992 in “International Journal of Dermatology” Minoxidil 2% effectively treats female hair loss, promoting growth and density.