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research Nudging hair shedding by antidandruff shampoos. A comparison of 1% ketoconazole, 1% piroctone olamine and 1% zinc pyrithione formulations

43 citations , October 2002 in “International Journal of Cosmetic Science”

This study found that 1% ketoconazole and 1% piroctone olamine shampoos increased hair shaft thickness and reduced hair shedding in men with telogen effluvium and androgenic alopecia associated with dandruff.

research The effects of minoxidil, 1% pyrithione zinc and a combination of both on hair density: a randomized controlled trial

57 citations , August 2003 in “British Journal of Dermatology”

This study found that daily use of 1% pyrithione zinc shampoo modestly improved hair growth over 26 weeks, although these effects were less than those of 5% minoxidil.

research A Comparison of Hair Quality and Cosmetic Acceptance Following the Use of Two Anti-Dandruff Shampoos

32 citations , November 2005 in “Journal of Investigative Dermatology Symposium Proceedings”

Most women preferred the 1% pyrithione zinc shampoo for better hair smoothness and less frizz while controlling dandruff.

research Does tachyphylaxis occur in long‐term management of scalp seborrheic dermatitis with pyrithione zinc‐based treatments?

16 citations , December 2008 in “International Journal of Dermatology”

This study concluded that no evidence of tachyphylaxis was found in the treatment of scalp seborrheic dermatitis and dandruff using pyrithione zinc-based shampoos over a 48-week period.

research Novel anti‐dandruff shampoo incorporated with ketoconazole‐coated zinc oxide nanoparticles using green tea extract

1 citations , November 2023 in “Journal of cosmetic dermatology”

This study developed a novel antidandruff shampoo with ketoconazole-coated zinc oxide nanoparticles that showed enhanced antifungal activity against Malassezia furfur compared to standard ketoconazole treatments, suggesting it could be a more effective alternative for dandruff management.

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community Ketoconazole shampoo has worked great for me. Those looking to take preventative measures should consider it.

in Ketoconazole 178 upvotes 1 year ago

Ketoconazole shampoo helps reduce hair shedding and improve thickness for some, but can cause dryness or irritation. Its effectiveness compared to finasteride or minoxidil varies among users.

community Taking Charge of Your Hair: The "Big 3 Stack" Explained for 2023

129 upvotes 3 years ago

The "Big 3 Stack" for hair loss treatment, which includes Minoxidil for hair density improvement, Ketoconazole shampoo for enhancing hair volume and thickness, and Finasteride for blocking hair loss causing hormones. Microneedling can boost Minoxidil's effects.

community DHT Harms Scalp Microbiome: DHT Itch is REAL

413 upvotes 1 year ago

Increased Malassezia and Cutibacterium in the scalp microbiome are linked to higher sebum production and inflammation in androgenetic alopecia (AGA). Treatments include ciclopirox shampoo, benzoyl peroxide shampoo, clobetasol propionate, calcipotriol, minoxidil, finasteride, and dutasteride.

community Microneedling + topical minoxidil is the most underrated combo.

439 upvotes 1 year ago

Microneedling with topical minoxidil is effective for hair regrowth, especially with finasteride. Users report fewer side effects compared to oral minoxidil.

community Guys, we finally have an alternative to finasteride

in Research/Science 263 upvotes 1 year ago

A combination of pyrilutamide, minoxidil, and alfatradiol is proposed as an effective alternative to finasteride for treating mild to moderate hair loss, claiming to stabilize hair loss and improve thickness without finasteride's side effects. Some users are skeptical about the effectiveness and approval of these treatments, while others are interested in trying them due to finasteride's side effects.

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learn Pyrithione Zinc

Can pyrithione zinc be combined with other active ingredients like ketoconazole or minoxidil? In one 26-week trial, adding zinc pyrithione shampoo to minoxidil gave no extra hair growth (Berger et al., Br J Dermatol 2003). Ask a pharmacist before combining medicated shampoos with a hair-loss medicine.
How does pyrithione zinc help reduce dandruff and irritation related to hair loss? In small controlled studies, zinc pyrithione shampoo reduced dandruff; lab studies suggest it works by slowing the growth of Malassezia yeast. It has not been shown to treat hair loss.
Is it okay to use pyrithione zinc daily, or should it be alternated with a gentle cleanser? US labels for zinc pyrithione dandruff shampoos say to use them at least twice a week, and studies have tested daily use for up to 26 weeks. In the EU, zinc pyrithione has been banned in cosmetics since 2022 because it is classified as toxic for reproduction, so ask a pharmacist if you are pregnant or trying to conceive.
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