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research Effects of Shampoo Containing Plantago asiatica L. on Hair Thickness, Density, and Shedding: A Double-Blind, Randomized, Placebo-Controlled Clinical Study

April 2025 in “Cosmetics”

In this randomized, double-blind study, a shampoo containing Plantago asiatica L. significantly improved hair thickness and density while reducing hair loss over 12 weeks in adults compared to a placebo.

research Double-blind randomized placebo-controlled study of the efficacy and safety of hair loss prevention shampoo containing salicylic acid, panthenol, and niacinamide in alopecia patients

1 citations , April 2022 in “Toxicology and Environmental Health Sciences”

This double-blind randomized placebo-controlled study found that a shampoo containing salicylic acid, panthenol, and niacinamide significantly increased hair count and improved hair loss symptoms in alopecia patients over 24 weeks, compared to a placebo, with no abnormal symptoms reported.

research The effect of minoxidil 1 shampoo on androgenetic alopecia: A clinical trial study

January 2016

This study found no significant difference in hair outcomes between patients using Minoxidil 1 shampoo and a placebo shampoo for alopecia over four months.

research A proprietary herbal extract against hair loss in androgenetic alopecia and telogen effluvium: a placebo-controlled, single-blind, clinical-instrumental study

1 citations , January 2018 in “Acta dermatovenerologica Alpina, Pannonica et Adriatica (Tiskana izd.)”

This study found that a herbal shampoo and solution were more effective than placebo in reducing hair loss and improving hair growth in participants with androgenetic alopecia and telogen effluvium.

research Scalp application of the antioxidant piroctone olamine reduces hair shedding in an 8‐week randomized, double‐blind, placebo‐controlled clinical study

1 citations , August 2021 in “International journal of cosmetic science (Print)”

This study reported that using piroctone olamine in either a shampoo or leave-on product form significantly increased hair retention and improved scalp condition in women with perceived hair thinning.

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Community Join

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community Am I getting results or is this just a placebo?

in Progress Pictures 9 upvotes 1 year ago

The conversation is about a user sharing their 40-day progress using dutasteride, topical Minoxidil, keto shampoo, and dermapen for hair loss, seeking opinions on whether the results are real or a placebo effect. Most responses suggest it's too early to see significant results and recommend continuing the treatment for 6-12 months for noticeable changes.

community Can shampoos be effective? An ad popping up on YouTube

in Treatment 7 months ago

Shampoos are not effective for stopping hair loss; treatments like minoxidil, finasteride, and dutasteride are more effective. Ketoconazole shampoo may help with scalp inflammation but not directly with hair loss.

community Ketoconazole shampoo for early-stage shedding looks like working!

in Ketoconazole 33 upvotes 1 year ago

Ketoconazole shampoo may help with early-stage hair loss by stopping hair regression and promoting new hair growth, though its effectiveness as a DHT blocker is debated. Users report varying results, with some experiencing dryness and others seeing improvement when used 2-3 times a week.

community Caffeine really a DHT blocker or placebo?

in Research/Science 7 upvotes 2 years ago

Caffeine is not a proven DHT blocker and does not effectively treat hair loss. Minoxidil, finasteride, and RU58841 are more reliable treatments.

community 3 month on min. Started keto shampoo and dut topical

in Journals / Progress Pictures 82 upvotes 1 year ago

The user started using topical and oral minoxidil in December 2024, added keto shampoo in February 2025, and began using a topical mix of dutasteride and minoxidil. The keto shampoo helped with scalp itchiness, but the hairline looks the same, and existing hairs appear frail and thin.

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Learn

5 / 800 results

learn Neem Oil

natural substance from Neem tree with medicinal and pesticidal properties

learn Beta Polypeptide

learn Ketoconazole

antifungal with some anti-androgenic benefits, often used as a shampoo

learn HMI-115

much-hyped research compound targeting prolactin receptor in scalp

learn Valproic acid

an anticonvulsant repurposed for hair loss via histone inhibition

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Clinics

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Experts

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