Clinicopathologic Characteristics and Response to Treatment of Persistent Chemotherapy-Induced Alopecia in Breast Cancer Survivors

    September 2021 in “ JAMA Dermatology ”
    Bevin Bhoyrul, Leila Asfour, G. Lutz … Matthew Harries
    Studysummary This study reports that persistent chemotherapy-induced alopecia in breast cancer patients frequently resembles androgenetic alopecia, and treatment with minoxidil, alone or with antiandrogens, improved hair density in many cases.
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    Research cited in this study 28

    1. Safety of Low-Dose Oral Minoxidil for Hair Loss: A Multicenter Study of 1404 Patients Journal of The American Academy of Dermatology · 2021
    2. Spironolactone Use Does Not Increase the Risk of Female Breast Cancer Recurrence: A Retrospective Analysis Journal of The American Academy of Dermatology · 2020
    3. CDK4/6 Inhibition Mitigates Stem Cell Damage in a Novel Model for Taxane-Induced Alopecia EMBO Molecular Medicine · 2019
    4. Minoxidil 1 mg Oral Versus Minoxidil 5% Topical Solution for the Treatment of Female-Pattern Hair Loss: A Randomized Clinical Trial Journal of The American Academy of Dermatology · 2019
    5. Effectiveness and Safety of Low-Dose Oral Minoxidil in Male Androgenetic Alopecia Journal of The American Academy of Dermatology · 2019
    6. Assessment of Quality of Life and Treatment Outcomes of Patients With Persistent Postchemotherapy Alopecia JAMA Dermatology · 2019
    7. Permanent Chemotherapy-Induced Alopecia in Patients with Breast Cancer: A 3-Year Prospective Cohort Study ˜The œoncologist · 2018
    8. Persistent Major Alopecia Following Adjuvant Docetaxel for Breast Cancer: Incidence, Characteristics, and Prevention with Scalp Cooling Breast Cancer Research and Treatment · 2018
    9. Hair Disorders in Patients with Cancer Journal of The American Academy of Dermatology · 2018
    10. Lichen Planopilaris and Frontal Fibrosing Alopecia as Model Epithelial Stem Cell Diseases Trends in Molecular Medicine · 2018
    11. Endocrine Therapy-Induced Alopecia in Patients With Breast Cancer JAMA Dermatology · 2018
    12. Permanent Alopecia in Patients with Breast Cancer After Taxane Chemotherapy and Adjuvant Hormonal Therapy: Clinicopathologic Findings in a Cohort of 10 Patients Journal of The American Academy of Dermatology · 2017
    13. Hair Regrowth in Male and Female Pattern Hair Loss Does Not Involve the Conversion of Vellus Hair to Terminal Hair Experimental Dermatology · 2016
    14. Clinical and Histological Study of Permanent Alopecia After Bone Marrow Transplantation Anais Brasileiros de Dermatologia · 2015
    15. Treatment of Permanent Chemotherapy-Induced Alopecia with Low Dose Oral Minoxidil Australasian Journal of Dermatology · 2015
    16. Permanent Chemotherapy-Induced Nonscarring Alopecia and Premature Ovarian Failure Clinical and Experimental Dermatology · 2015
    17. Analysis of Quantitative Changes in Hair Growth During Treatment With Chemotherapy or Tamoxifen in Patients With Breast Cancer: A Cohort Study British Journal of Dermatology · 2013
    18. Alopecia With Endocrine Therapies in Patients With Cancer Oncologist · 2013
    19. Dermal Papilla Cell Number Specifies Hair Size, Shape, and Cycling, and Its Reduction Causes Follicular Decline Development · 2013
    20. Pathobiology of Chemotherapy-Induced Hair Loss The Lancet Oncology · 2013
    21. Permanent Scalp Alopecia Related to Breast Cancer Chemotherapy by Sequential Fluorouracil/Epirubicin/Cyclophosphamide (FEC) and Docetaxel: A Prospective Study of 20 Patients Annals of Oncology · 2012
    22. Chemotherapy-Induced Alopecia Journal of the American Academy of Dermatology · 2011
    23. Impact of Taxol on Dermal Papilla Cells: A Proteomics and Bioinformatics Analysis Journal of proteomics · 2011
    24. Permanent Alopecia After Systemic Chemotherapy: A Clinicopathological Study of 10 Cases The American Journal of Dermatopathology · 2011
    25. Bald Scalp in Men with Androgenetic Alopecia Retains Hair Follicle Stem Cells but Lacks CD200-Rich and CD34-Positive Hair Follicle Progenitor Cells Journal of Clinical Investigation · 2011
    26. Permanent Chemotherapy-Induced Alopecia: Case Report and Review of the Literature Journal of The American Academy of Dermatology · 2010
    27. Dissecting the Impact of Chemotherapy on the Human Hair Follicle ˜The œAmerican journal of pathology · 2007
    28. The Reliability of Horizontally Sectioned Scalp Biopsies in the Diagnosis of Chronic Diffuse Telogen Hair Loss in Women Journal of The American Academy of Dermatology · 2004

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    2. Sensitive Scalp: An Epidemiologic Study in Patients with Hair Loss Dermatology Reports · 2022
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    4. Psoriatic Alopecia in a Patient with Systemic Lupus Erythematosus Case Reports in Dermatology · 2017
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