Clinicopathologic Characteristics and Response to Treatment of Persistent Chemotherapy-Induced Alopecia in Breast Cancer Survivors

    November 2021 in “ JAMA Dermatology
    Bevin Bhoyrul, Leila Asfour, G. Lutz, Lara Mitchell, Rebekka Jerjen, Rodney Sinclair, Susan Holmes, Iskander H. Chaudhry, Matthew Harries
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    TLDR Different types of persistent hair loss after chemotherapy respond differently to treatments.
    The document discusses a study involving 112 breast cancer survivors with persistent chemotherapy-induced alopecia (PCIA). The study found that 63% of the participants had pattern alopecia, while 37% had alopecia areata-like. Minoxidil and spironolactone treatments improved hair density in 75% of the participants with pattern alopecia, but were less effective in those with alopecia areata-like, with only 21% showing improvement. The study concludes that the type of PCIA can influence the effectiveness of treatment, and further research is needed to develop more effective treatments for all types of PCIA.
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