Permanent Alopecia in Patients with Breast Cancer After Taxane Chemotherapy and Adjuvant Hormonal Therapy: Clinicopathologic Findings in a Cohort of 10 Patients
March 2017
in “
Journal of The American Academy of Dermatology
”
permanent alopecia taxane chemotherapy adjuvant hormonal therapy alopecia areata-like female pattern hair loss hair follicle units reduced hair density telogen hair follicles vellus hair follicles pigment casts peribulbar lymphoid cell infiltrate hair follicle cycle follicle miniaturization topical minoxidil permanent hair loss taxane hormonal therapy female pattern baldness hair follicles hair density telogen phase vellus hair minoxidil
Studysummary This study observed various patterns of permanent alopecia in breast cancer patients treated with taxanes and adjuvant hormonal chemotherapy, hypothesizing disruptions in hair follicle cycles due to chemoinflammatory and hormonal factors.
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