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Glossary Pigment Casts

cylindrical structures in hair follicles containing melanin

Pigment casts are cylindrical structures found in hair follicles that contain melanin, the pigment responsible for hair color. They can be observed under a microscope and are often associated with certain hair disorders, such as trichotillomania (hair-pulling disorder) or alopecia areata, where they indicate abnormal hair growth or damage.

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Research

5 / 1000+ results

research Leucoderma Associated with the Use of Topical Minoxidil: A Report of Two Cases

15 citations , January 2000 in “Dermatology”

This case report describes two patients who developed leucoderma on the scalp after using 2% minoxidil lotion, with repigmentation occurring after discontinuation.

research Lichen Planus Pigmentosus in North Africa: A Series of 17 Cases

4 citations , November 2019 in “Dermatology - Open Journal”

This study reports that Lichen planus pigmentosus is present in Moroccan patients but remains challenging to treat, with only some experiencing complete resolution of lesions after therapy.

research Clinical and microscopic features of generalized discoid lupus erythematosus in dogs (10 cases)

20 citations , October 2016 in “Veterinary dermatology”

This study reports that generalized discoid lupus erythematosus is a recognized canine variant of cutaneous lupus erythematosus, resembling its human counterpart, with varied treatment responses and common relapses.

research Severe diffuse non-scarring hair loss in systemic lupus erythematosus - clinical and histopathological analysis of four cases

15 citations , December 2011 in “Journal of the European Academy of Dermatology and Venereology”

In this study, severe diffuse hair loss in patients with systemic lupus erythematosus was associated with distinct clinical, dermoscopic, and histopathological features, which improved alongside treatment of the underlying condition.

research Eosinophils in fibrous tracts and near hair bulbs: A helpful diagnostic feature of alopecia areata

64 citations , July 1997 in “Journal of The American Academy of Dermatology”

This study found that eosinophils are a useful diagnostic feature for alopecia areata, especially when the typical "swarm of bees" lymphoid infiltrate is absent, helping differentiate it from trichotillomania.

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Community Join

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community Stopped on fin, diffuse thinner, white hairs meaning

in Finasteride/Dutasteride 5 upvotes 1 month ago

The user stopped using finasteride and noticed diffuse thinning and white hairs on the crown, considering restarting finasteride and adding minoxidil. White hairs are miniaturized follicles that may regain pigment and thickness with treatment, and it's suggested to wait 12 months before considering a hair transplant.

community Why isn’t scalp micropigmentation (SMP) more popular?

in SMP 43 upvotes 1 year ago

Scalp micropigmentation (SMP) is a debated hair loss solution, with some praising its natural look and low maintenance, while others criticize it for looking unnatural and being a temporary fix. Many prefer traditional hair restoration methods like hair transplants or medications such as finasteride and minoxidil.

community New article on PP405..........

in Research/Science 109 upvotes 1 year ago

Scientists at UCLA have developed a promising treatment for male pattern baldness using a molecule called PP405, which can potentially stimulate dormant hair follicles. Initial trials showed significant results within a week, but larger clinical trials are needed to confirm its efficacy and safety.

community Prevention of age-related beard graying in humans by the topical application of Eriodictyon angustifolium extract

5 upvotes 4 years ago

Topical application of Eriodictyon angustifolium extract can prevent and reverse age-related beard graying and darken gray hair by increasing melanin production. Sterubin, a component of the extract, also promotes hair pigmentation and protects cells from DNA damage.

community UVA researchers discovered stem cells that plays a crucial role in hair growth - We are closer than ever to the cure!

281 upvotes 1 year ago

Researchers at the University of Virginia discovered a new group of stem cells in hair follicles that could potentially restore hair growth. The findings suggest that activating these stem cells might offer a new way to combat hair loss, though practical treatments are still years away.

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Learn

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learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

learn Overview

learn Scalp Micropigmentation

What pigments are used in scalp micropigmentation? Providers describe SMP pigments as organic, vegan and formulated for the scalp, but these are supplier and marketing descriptions rather than verified specifications, and clinics contradict each other on colour change and chemical content.
Are the pigments used in scalp micropigmentation safe? Providers describe SMP pigments as safe, medical-grade and made for the scalp, but those are supplier and clinic descriptions rather than regulatory approvals: no colour additive is approved for injection into the skin, and allergic reactions to tattoo pigment are documented.

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Clinics

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