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GlossaryPermanent Alopecia

permanent hair loss due to damaged or destroyed hair follicles

Permanent Alopecia, also known as irreversible alopecia or permanent hair loss, refers to the long-term or lifelong loss of hair from the scalp or other parts of the body. This condition can result from various causes, including genetic factors (such as androgenetic alopecia), scarring from injuries or medical treatments (like radiation therapy), and certain autoimmune diseases (such as alopecia areata that progresses to a scarring form). Unlike temporary hair loss, the hair follicles in permanent alopecia are often damaged or destroyed, making regrowth impossible.

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Research

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research Pitfalls of Midface Surgery

5 citations, August 2005 in “Facial Plastic Surgery Clinics of North America”

Midface surgery complications are generally rare and manageable with skilled surgery and informed patients.

research Six Cases of Permanent Alopecia After Various Conditioning Regimens Commonly Used in Hematopoietic Stem Cell Transplantation

40 citations, September 2007 in “Bone marrow transplantation”

Certain chemotherapy drugs can cause permanent hair loss in stem cell transplant patients.

research Hair Loss: An Overview

9 citations, August 2001 in “PubMed”

Hair loss can often be reversed with the right treatment.

research Increasing Tinea Capitis Prevalence in Stockholm Reflects Immigration

52 citations, January 2004 in “Medical mycology”

The rise in tinea capitis cases in Stockholm is linked to increased African immigration.

research Systematic Review of the Risk of Permanent Alopecia with Docetaxel Treatment for Breast Cancer

January 2016 in “Journal of clinical case reports”

Docetaxel treatment for breast cancer can cause permanent hair loss.

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community Can low level of vitamins cause hair loss?

in Research/Science 22 upvotes 1 year ago

The conversation is about whether low vitamin levels can cause hair loss. The consensus is that the user's vitamin levels are normal and unlikely to affect hair loss or the effectiveness of finasteride and minoxidil treatments.

community Proof that finasteride messes with neurosteroids

in Research/Science 230 upvotes 7 months ago

Finasteride can impact neurosteroids, potentially causing depression and other side effects in some users. Despite these concerns, many continue using it for hair loss, with some switching to topical applications to mitigate side effects.

community My Theory Regarding a Cause and Cure for Androgenetic Alopecia

in Treatment 97 upvotes 5 years ago

Hair loss theory suggests imbalance between Vitamin D Receptor (VDR) and Androgen Receptor (AR) activation. Proposed treatment includes upregulating VDR, downregulating AR, and improving mitochondrial health.

community Lost density 60% all over scalp in 120 days (4months)

in Update 10 upvotes 8 months ago

A user lost 60% hair density in 4 months, started finasteride and microneedling, and has greasy, flaky, yellowish scalp. They are awaiting biopsy results, and another user suggested trying ketoconazole shampoo.

community scarring alopecia awareness in this community

in Chat 33 upvotes 2 years ago

Lichen Planopilaris (LPP), a form of permanent hair loss, which can be mistaken for seborrheic dermatitis and is characterized by scalp itching, burning, redness, and dandruff. Treatment options discussed include steroidal creams, finasteride, minoxidil, and RU58841.

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