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    Glossary Permanent Alopecia

    permanent hair loss due to damaged or destroyed hair follicles

    Permanent Alopecia, also known as irreversible alopecia or permanent hair loss, refers to the long-term or lifelong loss of hair from the scalp or other parts of the body. This condition can result from various causes, including genetic factors (such as androgenetic alopecia), scarring from injuries or medical treatments (like radiation therapy), and certain autoimmune diseases (such as alopecia areata that progresses to a scarring form). Unlike temporary hair loss, the hair follicles in permanent alopecia are often damaged or destroyed, making regrowth impossible.

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    1. Permanent alopecia after cranial irradiation: Dose–response relationship International journal of radiation oncology, biology, physics · 2004 · 120 citations
    2. Female Pattern Hair Loss and its Relationship to Permanent/Cicatricial Alopecia: A New Perspective Journal of Investigative Dermatology Symposium Proceedings · 2005 · 73 citations
    3. Permanent scalp alopecia related to breast cancer chemotherapy by sequential fluorouracil/epirubicin/cyclophosphamide (FEC) and docetaxel: a prospective study of 20 patients Annals of Oncology · 2012 · 68 citations
    4. Permanent alopecia following chemotherapy and bone marrow transplantation Australasian Journal of Dermatology · 2000 · 63 citations
    5. Permanent Alopecia After Systemic Chemotherapy: A Clinicopathological Study of 10 Cases The American Journal of Dermatopathology · 2011 · 57 citations
    6. Permanent alopecia in patients with breast cancer after taxane chemotherapy and adjuvant hormonal therapy: Clinicopathologic findings in a cohort of 10 patients Journal of The American Academy of Dermatology · 2017 · 31 citations
    7. Lipedematous alopecia: an uncommon clinicopathologic variant of nonscarring but permanent alopecia International Journal of Dermatology · 2008 · 30 citations
    8. Clinical and histological study of permanent alopecia after bone marrow transplantation Anais Brasileiros de Dermatologia · 2015 · 23 citations
    9. Permanent diffuse alopecia after haematopoietic stem cell transplantation in childhood Bone Marrow Transplantation · 2017 · 16 citations
    10. Radiation- and Chemotherapy-Induced Permanent Alopecia: Case Series Journal of Cutaneous Medicine and Surgery · 2013 · 14 citations
    11. Postoperative permanent pressure alopecia Journal of anesthesia · 2015 · 13 citations
    12. Docetaxel and permanent alopecia Journal of The American Academy of Dermatology · 2013 · 8 citations
    13. Permanent chemotherapy-induced nonscarring alopecia and premature ovarian failure Clinical and Experimental Dermatology · 2015 · 5 citations
    14. Permanent chemotherapy-induced alopecia after hematopoietic stem cell transplantation treated with low-dose oral minoxidil JAAD case reports · 2022 · 4 citations
    15. Drug-induced scarring and permanent alopecia JAAD reviews. · 2024 · 2 citations
    16. Permanent Alopecia in Breast Cancer Patients: Role of Taxanes and Endocrine Therapies Cutis · 2021 · 2 citations
    17. Permanent alopecia as a manifestation of chronic graft-versus-host disease of the scalp: clinical, dermoscopic and histopathological observations Clinical and Experimental Dermatology · 2018 · 2 citations
    18. Systematic Review of the Risk of Permanent Alopecia with Docetaxel Treatment for Breast Cancer Journal of clinical case reports · 2016
    19. Corrections to “Female Pattern Hair Loss and its Relationship to Permanent/Cicatricial Alopecia: A New Perspective” Journal of Investigative Dermatology · 2007
    20. A case report of alopecia totalis associated with permanent hair dye use JAAD case reports · 2020 · 4 citations
    21. Chemotherapy-Induced Eyebrow Alopecia and Psychological Recovery: Permanent Micropigmentation as a Component of Multidisciplinary Oncological Rehabilitation 2026
    22. Permanent chemotherapy-induced alopecia: Case report and review of the literature Journal of The American Academy of Dermatology · 2010 · 67 citations
    23. Scalp Segmentation and Permanent Alopecia Prediction in Pediatric Craniospinal Irradiation: The PAST and HOPE Projects EJC Paediatric Oncology · 2026
    24. Treatment of permanent chemotherapy-induced alopecia with low dose oral minoxidil Australasian Journal of Dermatology · 2015 · 36 citations
    25. Psychoemotional Outcomes of Permanent Eyebrow Correction in Patients with Alopecia and After Chemotherapy Universal library of medical and health sciences. · 2025
    26. Alopecia areata after severe allergic contact dermatitis to a permanent hair dye Contact dermatitis · 2022
    27. Alopécia Permanente Pós-Quimioterapia com Resposta Favorável ao Minoxidil Tópico Revista da Sociedade Portuguesa de Dermatologia e Venereologia · 2017
    28. Permanent Chemotherapy-Induced Alopecia in Patients with Breast Cancer: A 3-Year Prospective Cohort Study ˜The œoncologist · 2018 · 59 citations
    29. Pediatric Ewing's Sarcoma and Permanent Chemotherapy‐Induced Alopecia: A Case–Control Study Pediatric Dermatology · 2025
    30. 51895 Interim Analysis of Platelet-Rich Plasma (PRP) Treatment for Endocrine Therapy-Induced Alopecia (EIA) and Permanent Chemotherapy-Induced Alopecia (pCIA) in Breast Cancer Patients: A Randomized Controlled Trial Journal of the American Academy of Dermatology · 2024