The Skin Microenvironment: A Dynamic Regulator of Hair Follicle Development, Cycling, and Disease

Research cited in this study 85

1. Functional Regeneration Strategies of Hair Follicles: Advances and Challenges Stem Cell Research & Therapy · 2025
2. Effects of Oral Minoxidil on Serum VEGF and Hair Regrowth in Androgenetic Alopecia Acta Dermatovenerologica Alpina Pannonica et Adriatica · 2025
3. Intermittent Fasting Triggers Interorgan Communication To Suppress Hair Follicle Regeneration Cell · 2024
4. TLR9 Activation in Large Wound Induces Tissue Repair and Hair Follicle Regeneration via γδT Cells Cell Death and Disease · 2024
5. Dermal TRPV1 Innervations Engage a Macrophage- and Fibroblast-Containing Pathway to Activate Hair Growth in Mice Developmental Cell · 2024
6. Melatonin Promotes Hair Regeneration by Modulating the Wnt/β-Catenin Signaling Pathway Cell proliferation · 2024
7. Metabolomics Reveals Metabolites Associated with Hair Follicle Cycle in Cashmere Goats BMC veterinary research · 2024
8. Crosstalk Between Endothelial Cells and Dermal Papilla Entails Hair Regeneration and Angiogenesis During Aging Journal of Advanced Research · 2024
9. Hydrogel Forming Microneedles Loaded With VEGF and Ritlecitinib/Polyhydroxyalkanoates Nanoparticles for Mini-Invasive Androgenetic Alopecia Treatment Bioactive materials · 2024
10. Interleukin-15 Is a Hair Follicle Immune Privilege Guardian Journal of Autoimmunity · 2024
11. Vitamin A Resolves Lineage Plasticity to Orchestrate Stem Cell Lineage Choices Science · 2024
12. Autophagy Induces Hair Follicle Stem Cell Activation and Hair Follicle Regeneration by Regulating Glycolysis 2024
13. Multiscale Spatial Mapping of Cell Populations Across Anatomical Sites in Healthy Human Skin and Basal Cell Carcinoma Proceedings of the National Academy of Sciences of the United States of America · 2024
14. Local and Systemic Mechanisms That Control the Hair Follicle Stem Cell Niche Nature Reviews Molecular Cell Biology · 2023
15. Incorporation of Hair Follicles in 3D Bioprinted Models of Human Skin Science Advances · 2023
16. Recent Omics Advances In Hair Aging Biology And Hair Biomarkers Analysis Ageing Research Reviews · 2023
17. Hdac1 and Hdac2 Regulate the Quiescent State and Survival of Hair-Follicle Mesenchymal Niche Nature communications · 2023
18. Effect of Fibroblast Growth Factor 10 and an Interacting Non-Coding RNA on Secondary Hair Follicle Dermal Papilla Cells in Cashmere Goats' Follicle Development Assessed by Whole-Transcriptome Sequencing Technology Animals · 2023
19. Hypoxia Treatment of Adipose Mesenchymal Stem Cells Promotes the Growth of Dermal Papilla Cells via HIF-1α and ERK1/2 Signaling Pathways International Journal of Molecular Sciences · 2023
20. Signaling by Senescent Melanocytes Hyperactivates Hair Growth Nature · 2023
21. Melatonin Promotes the Development of Secondary Hair Follicles in Adult Cashmere Goats by Activating the Keap1-Nrf2 Signaling Pathway and Inhibiting the Inflammatory Transcription Factors NFkB and AP-1 International Journal of Molecular Sciences · 2023
22. Commensal Microbiome Promotes Hair Follicle Regeneration by Inducing Keratinocyte HIF-1α Signaling and Glutamine Metabolism Science Advances · 2023
23. Single-Cell Profiling Reveals a Potent Role of Quercetin in Promoting Hair Regeneration Protein & Cell · 2022
24. Randomized Trial of Microneedling Combined With 2% Minoxidil Topical Solution for the Treatment of Female Pattern Hair Loss in a Chinese Population Journal of Cosmetic Dermatology · 2022
25. A Comprehensive Review of Microneedling as a Potential Treatment Option for Androgenetic Alopecia Aesthetic Plastic Surgery · 2022
26. Hedgehog Signaling Reprograms Hair Follicle Niche Fibroblasts to a Hyper-Activated State Developmental cell · 2022
27. 3D Bioprinting of a Gelatin-Alginate Hydrogel for Tissue-Engineered Hair Follicle Regeneration Acta Biomaterialia · 2022
28. Oral Minoxidil Use in Androgenetic Alopecia and Telogen Effluvium Archives of Dermatological Research · 2022
29. A Systematic Summary of Survival and Death Signaling During the Life of Hair Follicle Stem Cells Stem Cell Research & Therapy · 2021
30. Corticosterone Inhibits GAS6 to Govern Hair Follicle Stem-Cell Quiescence Nature · 2021
31. Functional Hair Follicle Regeneration: An Updated Review Signal Transduction and Targeted Therapy · 2021
32. Dermal Adipose Tissue Secretes HGF to Promote Human Hair Growth and Pigmentation Journal of Investigative Dermatology · 2021
33. Hair Follicle Germs Containing Vascular Endothelial Cells for Hair Regenerative Medicine Scientific Reports · 2021
34. Multiple Potential Roles of Thymosin Beta 4 in the Growth and Development of Hair Follicles Journal of Cellular and Molecular Medicine · 2021
35. Generation of VEGF Knock-In Cashmere Goat via the CRISPR/Cas9 System International Journal of Biological Sciences · 2021
36. Glutamine Metabolism Controls Stem Cell Fate Reversibility and Long-Term Maintenance in the Hair Follicle Cell Metabolism · 2020
37. Induction of Dermal Fibroblasts into Dermal Papilla Cell-Like Cells in Hydrogel Microcapsules for Enhanced Hair Follicle Regeneration Applied Materials Today · 2020
38. Hair-Bearing Human Skin Generated Entirely From Pluripotent Stem Cells Nature · 2020
39. Jagged1 and Epidermal Growth Factor Promoted Androgen-Suppressed Mouse Hair Growth In Vitro and In Vivo Frontiers in Pharmacology · 2020
40. Hyperactivation of Sympathetic Nerves Drives Depletion of Melanocyte Stem Cells Nature · 2020
41. Hes1 Regulates Anagen Initiation and Hair Follicle Regeneration Through Modulation of Hedgehog Signaling Stem Cells · 2019
42. Lymphatic Vessels Interact Dynamically with the Hair Follicle Stem Cell Niche During Skin Regeneration In Vivo The EMBO Journal · 2019
43. Vascular Endothelial Growth Factor Protects CD200-Rich and CD34-Positive Hair Follicle Stem Cells Against Androgen-Induced Apoptosis Through the Phosphoinositide 3-Kinase/Akt Pathway in Patients With Androgenic Alopecia Dermatologic Surgery · 2019
44. Stimulation of Hair Growth by Small Molecules That Activate Autophagy Cell reports · 2019
45. TREM2+ Macrophages Inhibit Hair Growth by Producing Oncostatin M Cell Stem Cell · 2019
46. A Subset of TREM2+ Dermal Macrophages Secretes Oncostatin M to Maintain Hair Follicle Stem Cell Quiescence and Inhibit Hair Growth Cell Stem Cell · 2019
47. Conditioned Media Derived from Mesenchymal Stem Cell Cultures: The Next Generation for Regenerative Medicine Journal of Tissue Engineering and Regenerative Medicine · 2019
48. The Role of Immature and Mature Adipocytes in Hair Cycling Trends in Endocrinology and Metabolism · 2018
49. The Role of Vitamins and Minerals in Hair Loss: A Review Dermatology and Therapy · 2018
50. A Novel and Safe Small Molecule Enhances Hair Follicle Regeneration by Facilitating Metabolic Reprogramming Experimental and Molecular Medicine · 2018
51. Emerging Nonmetabolic Functions of Skin Fat Nature Reviews Endocrinology · 2018
52. The Role of Vitamin D in Non-Scarring Alopecia International Journal of Molecular Sciences · 2017
53. Evidence-Based Guideline for the Treatment of Androgenetic Alopecia in Women and Men – Short Version Journal of The European Academy of Dermatology and Venereology · 2017
54. Mesenchymal Stem Cell Secretome: Toward Cell-Free Therapeutic Strategies in Regenerative Medicine International Journal of Molecular Sciences · 2017
55. Low-Level Light and Minoxidil 5% Combination Versus Either Modality Alone in Management of Female Patterned Hair Loss: A Randomized Controlled Study Lasers in Surgery and Medicine · 2017
56. Platelet-Derived Growth Factor Signaling Modulates Adult Hair Follicle Dermal Stem Cell Maintenance and Self-Renewal npj Regenerative Medicine · 2017
57. Macrophages Induce AKT/β-Catenin-Dependent Lgr5+ Stem Cell Activation and Hair Follicle Regeneration Through TNF Nature Communications · 2017
58. Epidermal Growth Factor Induces Proliferation of Hair Follicle-Derived Mesenchymal Stem Cells Through Epidermal Growth Factor Receptor-Mediated Activation of ERK and AKT Signaling Pathways Associated With Upregulation of Cyclin D1 and Downregulation of p16 Stem Cells and Development · 2016
59. Bioengineering a 3D Integumentary Organ System from iPS Cells Using an In Vivo Transplantation Model Science Advances · 2016
60. Hair Follicle Aging Is Driven by Transepidermal Elimination of Stem Cells via COL17A1 Proteolysis Science · 2016
61. Repeated Microneedle Stimulation Induces Enhanced Hair Growth in a Murine Model Annals of Dermatology · 2016
62. Rethinking Regeneration: Empowerment of Stem Cells by Inflammation Cell Death & Differentiation · 2015
63. Pharmacologic Inhibition of JAK-STAT Signaling Promotes Hair Growth Science Advances · 2015
64. Macrophages Contribute to the Cyclic Activation of Adult Hair Follicle Stem Cells PLoS Biology · 2014
65. Resting No More: Redefining Telogen, the Maintenance Stage of the Hair Growth Cycle Biological Reviews · 2014
66. Novel Mechanisms for the Vitamin D Receptor in the Skin and in Skin Cancer The Journal of Steroid Biochemistry and Molecular Biology · 2014
67. Adipocytes in Skin Health and Disease Cold Spring Harbor Perspectives in Medicine · 2014
68. Cyclosporine A Stimulated Hair Growth from Mouse Vibrissae Follicles in an Organ Culture Model Journal of Nanjing Medical University · 2012
69. Stress-Induced Production of Chemokines by Hair Follicles Regulates the Trafficking of Dendritic Cells in Skin Nature Immunology · 2012
70. VEGF Induces Proliferation of Human Hair Follicle Dermal Papilla Cells Through VEGFR-2-Mediated Activation of ERK Experimental Cell Research · 2012
71. Successful Treatment of Alopecia Areata with Topical Calcipotriol Annals of dermatology/Annals of Dermatology · 2012
72. Dihydrotestosterone-Inducible IL-6 Inhibits Elongation of Human Hair Shafts by Suppressing Matrix Cell Proliferation and Promotes Regression of Hair Follicles in Mice Journal of Investigative Dermatology · 2011
73. Adipocyte Lineage Cells Contribute to the Skin Stem Cell Niche to Drive Hair Cycling Cell · 2011
74. Current Standards in the Diagnostics and Therapy of Hair Diseases - Hair Consultation Journal der Deutschen Dermatologischen Gesellschaft · 2011
75. The Basement Membrane Of Hair Follicle Stem Cells Is A Muscle Cell Niche Cell · 2011
76. Microenvironmental Reprogramming of Thymic Epithelial Cells to Skin Multipotent Stem Cells Nature · 2010
77. Nutrition and Hair Health: The Impact of Nutritional Deficiencies Clinics in Dermatology · 2010
78. Cutaneous Consequences of Inhibiting EGF Receptor Signaling In Vivo: Normal Hair Follicle Development, But Retarded Hair Cycle Induction and Inhibition of Adipocyte Growth in EgfrWa5 Mice Journal of Dermatological Science · 2010
79. Thyrotropin Releasing Hormone: A New Player in Human Hair Growth Control ˜The œFASEB journal · 2009
80. Human Female Hair Follicles Are a Direct, Nonclassical Target for Thyroid-Stimulating Hormone Journal of Investigative Dermatology · 2008
81. Towards New Aspects of Melatonin Research in Dermato-Endocrinology Experimental dermatology · 2008
82. Maintenance of Hair Follicle Immune Privilege Is Linked to Prevention of NK Cell Attack Journal of Investigative Dermatology · 2007
83. Prolactin Delays Hair Regrowth in Mice Journal of Endocrinology · 2006
84. Keratin 15 Promoter Targets Putative Epithelial Stem Cells in the Hair Follicle Bulge Journal of Investigative Dermatology · 2003
85. Keratinocyte Growth Factor Is an Important Endogenous Mediator of Hair Follicle Growth, Development, and Differentiation. Normalization of the Nu/Nu Follicular Differentiation Defect and Amelioration of Chemotherapy-Induced Alopecia. PubMed · 1995